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Hematology&Oncology
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Reactive cysteines on peptide antigens may unlock new cancer immunotherapy possibilities

Reactive cysteines on peptide antigens may unlock new cancer immunotherapy possibilities

by Olivia Dimmer,Northwestern UniversityDevelopment of cell-impermeable cysteine-reactive probes. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54139-8Northwestern Medi

Reactive cysteines on peptide antigens may unlock new cancer immunotherapy possibilities

by Olivia Dimmer,Northwestern UniversityDevelopment of cell-impermeable cysteine-reactive probes. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54139-8Northwestern Medi
Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemiaby Markus Bernards,Goethe University Frankfurt am MainGeneration process and evaluation of CRISPR/Cas9 knockout for CAR3

Engineered CAR-NK cells offer an alternative approach to fighting leukemia

Engineered CAR-NK cells offer an alternative approach to fighting leukemiaby Markus Bernards,Goethe University Frankfurt am MainGeneration process and evaluation of CRISPR/Cas9 knockout for CAR3
Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi

Reducing dose of popular blood thinners may limit risk of future bleeding, study finds

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainFor people taking popular blood thinners after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospi
How breast cancer cells survive in bone marrow after remission

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive
Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th
Researchers explore e-bikes for cancer recovery

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT:

Researchers explore e-bikes for cancer recovery

by Patty Wellborn,University of British ColumbiaOutline of the CRANK intervention development. APEASE: Acceptability, Practicability, Effectiveness, Affordability, Side-Effects, and Equity; BCT:
Neurocognitive battery feasible in 3-year-olds during leukemia treatment

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri
Survival rates for incurable larynx cancer investigated for first time

Survival rates for incurable larynx cancer investigated for first time

byNewcastle UniversityKaplan Meier Survival Curves with associated estimated survival rates for entire cohort. Credit:Clinical Otolaryngology(2024). DOI: 10.1111/coa.14260First-of-it

Survival rates for incurable larynx cancer investigated for first time

byNewcastle UniversityKaplan Meier Survival Curves with associated estimated survival rates for entire cohort. Credit:Clinical Otolaryngology(2024). DOI: 10.1111/coa.14260First-of-it
Natural killer cells offer hope for hard-to-treat pediatric sarcomas

Natural killer cells offer hope for hard-to-treat pediatric sarcomas

byUniversity of QueenslandEphrin type-A receptor-2 (EphA2) and natural killer (NK) cell infiltration correspond with sarcoma survival. Credit:Clinical and Translational Medicine(2025

Natural killer cells offer hope for hard-to-treat pediatric sarcomas

byUniversity of QueenslandEphrin type-A receptor-2 (EphA2) and natural killer (NK) cell infiltration correspond with sarcoma survival. Credit:Clinical and Translational Medicine(2025