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Hematology&Oncology
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New understanding of T cell receptors may improve cancer immunotherapies

New understanding of T cell receptors may improve cancer immunotherapies

byRockefeller UniversityThe gray portion of this schematic represents a nanodisk, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell rec

New understanding of T cell receptors may improve cancer immunotherapies

byRockefeller UniversityThe gray portion of this schematic represents a nanodisk, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell rec
Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a
Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their
New technology reduces false positives in breast ultrasounds

New technology reduces false positives in breast ultrasounds

byJohns Hopkins UniversityConventional ultrasound of breast tissue compared to the new method. Conventional ultrasound relies on the amplitude of signals, turning high and low signals into blacks, whi

New technology reduces false positives in breast ultrasounds

byJohns Hopkins UniversityConventional ultrasound of breast tissue compared to the new method. Conventional ultrasound relies on the amplitude of signals, turning high and low signals into blacks, whi
WISDOM trial weighs risk-based cancer screening

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based
Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

byMassachusetts Institute of TechnologyAbLecs enhance antibody effector functions via glyco-immune checkpoint blockade. Credit:bioRxiv. DOI: 10.1101/2022.10.26.513931Researchers at MIT and Stanford Un

Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

byMassachusetts Institute of TechnologyAbLecs enhance antibody effector functions via glyco-immune checkpoint blockade. Credit:bioRxiv. DOI: 10.1101/2022.10.26.513931Researchers at MIT and Stanford Un
Protein linked to cancer found to play key role in wound healing

Protein linked to cancer found to play key role in wound healing

by Richard Harth,Arizona State UniversityASU researchers Jordan Yaron and Kaushal Rege have found that the previously mysterious protein SerpinB3 plays a vital role in the body's natural wound-hea

Protein linked to cancer found to play key role in wound healing

by Richard Harth,Arizona State UniversityASU researchers Jordan Yaron and Kaushal Rege have found that the previously mysterious protein SerpinB3 plays a vital role in the body's natural wound-hea
Tracking RNA levels reveals new clues in triple-negative breast cancer progression

Tracking RNA levels reveals new clues in triple-negative breast cancer progression

by Jen A. Miller,Cold Spring Harbor LaboratoryMetastatic lesions had far higher levels ofMALAT1(pink) than the surrounding tissues. Credit: Spector lab/CSHLWhen researchers look for potential cancer t

Tracking RNA levels reveals new clues in triple-negative breast cancer progression

by Jen A. Miller,Cold Spring Harbor LaboratoryMetastatic lesions had far higher levels ofMALAT1(pink) than the surrounding tissues. Credit: Spector lab/CSHLWhen researchers look for potential cancer t
Pancreatic cancer forms 'synapses,' scientists discover

Pancreatic cancer forms 'synapses,' scientists discover

by Paul Hellmich,Technical University MunichImmunofluorescence image of pancreatic cancer cells that invade nerves: nerve cells appear in green, tumor cells in red. Credit: Ekin Demir / TUMPancreatic

Pancreatic cancer forms 'synapses,' scientists discover

by Paul Hellmich,Technical University MunichImmunofluorescence image of pancreatic cancer cells that invade nerves: nerve cells appear in green, tumor cells in red. Credit: Ekin Demir / TUMPancreatic
Medical patients face hidden time burdens: An overlooked cost of cancer care

Medical patients face hidden time burdens: An overlooked cost of cancer care

byUniversity of MinnesotaCredit: Pixabay/CC0 Public DomainTreatments for serious illnesses like cancer can be enormously time-consuming. Yet most research on cancer-related time burdens has relied on

Medical patients face hidden time burdens: An overlooked cost of cancer care

byUniversity of MinnesotaCredit: Pixabay/CC0 Public DomainTreatments for serious illnesses like cancer can be enormously time-consuming. Yet most research on cancer-related time burdens has relied on
Lab platform models human organs to test cancer drug toxicity without animals

Lab platform models human organs to test cancer drug toxicity without animals

byUniversity of GenevaDifferentiated hepatic cells growing in a flask re-gain the appearance of cells present in liver. Credit: FAMOL, UNIGEOvercoming acquired treatment resistance is one of the major

Lab platform models human organs to test cancer drug toxicity without animals

byUniversity of GenevaDifferentiated hepatic cells growing in a flask re-gain the appearance of cells present in liver. Credit: FAMOL, UNIGEOvercoming acquired treatment resistance is one of the major
How colorectal cancer evades immunotherapy using a dual barrier

How colorectal cancer evades immunotherapy using a dual barrier

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainColorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treat

How colorectal cancer evades immunotherapy using a dual barrier

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainColorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treat