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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
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Blood Types: What Letters, Positive, and Negative Signs Mean

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Blood Types: What Letters, Positive, and Negative Signs Mean

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Pembrolizumab Recommended for EU Approval in Hodgkin Lymphoma

Pembrolizumab Recommended for EU Approval in Hodgkin Lymphoma

March 24, 2017Jason M. BroderickThe EMA’s Committee for Medicinal Products for Human Use has recommended approval of pembrolizumab for the treatment of adult patients with relapsed or refractory class
World medicine November 21,2023
Pembrolizumab Recommended for EU Approval in Hodgkin Lymphoma

Pembrolizumab Recommended for EU Approval in Hodgkin Lymphoma

March 24, 2017Jason M. BroderickThe EMA’s Committee for Medicinal Products for Human Use has recommended approval of pembrolizumab for the treatment of adult patients with relapsed or refractory class
World medicine November 21,2023
Nivolumab Delivers Durable Responses in Hodgkin Lymphoma

Nivolumab Delivers Durable Responses in Hodgkin Lymphoma

June 6, 2016Jason M. BroderickSingle-agent nivolumab induced responses in 66% of patients with classical Hodgkin lymphoma who had progressed following autologous stem cell transplant and brentuximab v
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Nivolumab Delivers Durable Responses in Hodgkin Lymphoma

Nivolumab Delivers Durable Responses in Hodgkin Lymphoma

June 6, 2016Jason M. BroderickSingle-agent nivolumab induced responses in 66% of patients with classical Hodgkin lymphoma who had progressed following autologous stem cell transplant and brentuximab v
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Leveraging the Lectin Pathway in Endothelial Injury Syndromes

Leveraging the Lectin Pathway in Endothelial Injury Syndromes

August 31, 2020Caroline SeymourEleni Gavriilaki, MD, PhD, discusses the rationale for the lectin pathway as a therapeutic target in hematopoietic stem cell transplantation–associated thrombotic microa
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Leveraging the Lectin Pathway in Endothelial Injury Syndromes

Leveraging the Lectin Pathway in Endothelial Injury Syndromes

August 31, 2020Caroline SeymourEleni Gavriilaki, MD, PhD, discusses the rationale for the lectin pathway as a therapeutic target in hematopoietic stem cell transplantation–associated thrombotic microa
World medicine November 21,2023
Verastem Targets Cancer Stem Cells

Verastem Targets Cancer Stem Cells

October 8, 2013Onclive TeamCancer stem cells are an underlying cause of a tumor's ability to recur and metastasize even after initial treatment. Therefore, targeting those cancer stem cells could
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Verastem Targets Cancer Stem Cells

Verastem Targets Cancer Stem Cells

October 8, 2013Onclive TeamCancer stem cells are an underlying cause of a tumor's ability to recur and metastasize even after initial treatment. Therefore, targeting those cancer stem cells could
World medicine November 21,2023
Maintenance Lenalidomide May Improve Survival in Post-ASCT Myeloma

Maintenance Lenalidomide May Improve Survival in Post-ASCT Myeloma

August 1, 2016Jason M. BroderickMaintenance lenalidomide following frontline treatment with high-dose melphalan and autologous stem cell transplant reduced the risk of death by 26% versus placebo or n
World medicine November 21,2023
Maintenance Lenalidomide May Improve Survival in Post-ASCT Myeloma

Maintenance Lenalidomide May Improve Survival in Post-ASCT Myeloma

August 1, 2016Jason M. BroderickMaintenance lenalidomide following frontline treatment with high-dose melphalan and autologous stem cell transplant reduced the risk of death by 26% versus placebo or n
World medicine November 21,2023
Novel Therapies Likely to Change Role of Stem Cell Transplants in Blood Cancers

Novel Therapies Likely to Change Role of Stem Cell Transplants in Blood Cancers

January 15, 2016Andrew D. SmithMortality and morbidity both appear to be declining with the emergence of better antibiotics and growth factors, so hematologists are beginning to consider transplants f
World medicine November 21,2023
Novel Therapies Likely to Change Role of Stem Cell Transplants in Blood Cancers

Novel Therapies Likely to Change Role of Stem Cell Transplants in Blood Cancers

January 15, 2016Andrew D. SmithMortality and morbidity both appear to be declining with the emergence of better antibiotics and growth factors, so hematologists are beginning to consider transplants f
World medicine November 21,2023
Anti-PD-1 Antibody Pidilizumab Shows Promise in Diffuse Large B-Cell Lymphoma

Anti-PD-1 Antibody Pidilizumab Shows Promise in Diffuse Large B-Cell Lymphoma

January 17, 2014Tony Berberabe, MPHThe anti-PD-1 monoclonal antibody pidilizumab showed promising clinical activity and was safely administered to patients with diffuse large B-cell lymphoma after aut
World medicine November 21,2023
Anti-PD-1 Antibody Pidilizumab Shows Promise in Diffuse Large B-Cell Lymphoma

Anti-PD-1 Antibody Pidilizumab Shows Promise in Diffuse Large B-Cell Lymphoma

January 17, 2014Tony Berberabe, MPHThe anti-PD-1 monoclonal antibody pidilizumab showed promising clinical activity and was safely administered to patients with diffuse large B-cell lymphoma after aut
World medicine November 21,2023
Efforts Continue to Enhance Stem Cell Transplants

Efforts Continue to Enhance Stem Cell Transplants

March 1, 2018Angelica WelchCarlos R. Bachier, MD, discusses the evolution of stem cell transplantation as a treatment for patients with hematologic malignancies.Carlos R. Bachier, MDEven with recent s
World medicine November 21,2023
Efforts Continue to Enhance Stem Cell Transplants

Efforts Continue to Enhance Stem Cell Transplants

March 1, 2018Angelica WelchCarlos R. Bachier, MD, discusses the evolution of stem cell transplantation as a treatment for patients with hematologic malignancies.Carlos R. Bachier, MDEven with recent s
World medicine November 21,2023
Computer Model Personalizes Donor Selection for Stem Cell Transplants

Computer Model Personalizes Donor Selection for Stem Cell Transplants

August 31, 2016Amir Ahmed Toor, MDIn Partnership With:Investigators at Virginia Commonwealth University Massey Cancer Center are developing dynamical models that may allow clinicians to move beyond si
World medicine November 21,2023
Computer Model Personalizes Donor Selection for Stem Cell Transplants

Computer Model Personalizes Donor Selection for Stem Cell Transplants

August 31, 2016Amir Ahmed Toor, MDIn Partnership With:Investigators at Virginia Commonwealth University Massey Cancer Center are developing dynamical models that may allow clinicians to move beyond si
World medicine November 21,2023
Stem Cell Transplants in Hodgkin Lymphoma

Stem Cell Transplants in Hodgkin Lymphoma

January 21, 2015For High-Definition, ClickThe standard of care for an individual with Hodgkin lymphoma who fails induction chemotherapy is salvage chemotherapy followed by stem cell transplant, states
World medicine November 21,2023
Stem Cell Transplants in Hodgkin Lymphoma

Stem Cell Transplants in Hodgkin Lymphoma

January 21, 2015For High-Definition, ClickThe standard of care for an individual with Hodgkin lymphoma who fails induction chemotherapy is salvage chemotherapy followed by stem cell transplant, states
World medicine November 21,2023
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