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New NIPT-based method reveals 33 pathogenic copy number variations in the Duchenne muscular dystrophy gene

New NIPT-based method reveals 33 pathogenic copy number variations in the Duchenne muscular dystrophy gene

by BGI GenomicsThe spectrum of maternal CNVs detected in the DMD gene. Credit:Clinical and Translational Medicine(2024). DOI: 10.1002/ctm2.1706A recent large cohort study, conducted jointl

New NIPT-based method reveals 33 pathogenic copy number variations in the Duchenne muscular dystrophy gene

by BGI GenomicsThe spectrum of maternal CNVs detected in the DMD gene. Credit:Clinical and Translational Medicine(2024). DOI: 10.1002/ctm2.1706A recent large cohort study, conducted jointl
Understanding molecular drivers of lymphedema

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und
Subretinal adeno-associated virus T-cell inhibition: Exploring potential existence of anti-transgene immune responses

Subretinal adeno-associated virus T-cell inhibition: Exploring potential existence of anti-transgene immune responses

byMary Ann Liebert, IncCo-injection of AAV8 and HY peptides in rd10 mice induces a subretinal associated immune inhibition. Credit:Human Gene Therapy(2024). DOI: 10.1089/hum.2023.191

Subretinal adeno-associated virus T-cell inhibition: Exploring potential existence of anti-transgene immune responses

byMary Ann Liebert, IncCo-injection of AAV8 and HY peptides in rd10 mice induces a subretinal associated immune inhibition. Credit:Human Gene Therapy(2024). DOI: 10.1089/hum.2023.191
Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin
Study finds hospital-onset SARS-CoV-2 infection during omicron linked to morbidity

Study finds hospital-onset SARS-CoV-2 infection during omicron linked to morbidity

by Elana GotkineDuring the omicron era, hospital-onset severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remained associated with increased morbidity and mortality, according to a

Study finds hospital-onset SARS-CoV-2 infection during omicron linked to morbidity

by Elana GotkineDuring the omicron era, hospital-onset severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remained associated with increased morbidity and mortality, according to a
Osteoarthritis may double risk of speedy progression to severe multimorbidity, study finds

Osteoarthritis may double risk of speedy progression to severe multimorbidity, study finds

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainOsteoarthritis—a condition in which the protective cartilage on the ends of bones breaks down—may more than double the risk of speedy pr

Osteoarthritis may double risk of speedy progression to severe multimorbidity, study finds

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainOsteoarthritis—a condition in which the protective cartilage on the ends of bones breaks down—may more than double the risk of speedy pr
Guidelines developed for ankylosing spondylitis treatment

Guidelines developed for ankylosing spondylitis treatment

(HealthDay)—Evidence-based recommendations have been developed for treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). The guidelines were publish

Guidelines developed for ankylosing spondylitis treatment

(HealthDay)—Evidence-based recommendations have been developed for treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). The guidelines were publish
Peresolimab found to be efficacious for rheumatoid arthritis

Peresolimab found to be efficacious for rheumatoid arthritis

by Elana GotkinePeresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patien

Peresolimab found to be efficacious for rheumatoid arthritis

by Elana GotkinePeresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patien
An experimental vaccine against rheumatoid arthritis

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a
Patients with rheumatoid arthritis have increased anxiety during pandemic

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol
Examining real-world treatment patterns of psoriatic arthritis

Examining real-world treatment patterns of psoriatic arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainDespite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation

Examining real-world treatment patterns of psoriatic arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainDespite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation