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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
Dermatology August 14,2024
Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Blood Types: What Letters, Positive, and Negative Signs Mean

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Scientists describe a function for autophagy in germline stem-cell proliferation

Scientists describe a function for autophagy in germline stem-cell proliferation

byThe City University of New YorkRendering of wild-type and mutantC. elegansgonads stained with Phalloidin to visualize the actin cytoskeleton. Credit: Alicia MelendezScientists stud
World medicine November 30,2023
Scientists describe a function for autophagy in germline stem-cell proliferation

Scientists describe a function for autophagy in germline stem-cell proliferation

byThe City University of New YorkRendering of wild-type and mutantC. elegansgonads stained with Phalloidin to visualize the actin cytoskeleton. Credit: Alicia MelendezScientists stud
World medicine November 30,2023
CRISPR-powered 'cancer shredding' technique opens new possibility for treating most common and deadly brain cancer

CRISPR-powered 'cancer shredding' technique opens new possibility for treating most common and deadly brain cancer

byGladstone InstitutesCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113339The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive
World medicine November 30,2023
CRISPR-powered 'cancer shredding' technique opens new possibility for treating most common and deadly brain cancer

CRISPR-powered 'cancer shredding' technique opens new possibility for treating most common and deadly brain cancer

byGladstone InstitutesCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113339The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive
World medicine November 30,2023
Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants

Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants

by Zhang Nannan,Chinese Academy of SciencesRH27 regulates zygote division and stem cell homeostasis through miRNA biogenesis. Credit: IBCASAfter double fertilization, zygotic activation occurs t
World medicine November 30,2023
Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants

Scientists reveal role of RNA helicase in zygote activation and stem cell homeostasis in plants

by Zhang Nannan,Chinese Academy of SciencesRH27 regulates zygote division and stem cell homeostasis through miRNA biogenesis. Credit: IBCASAfter double fertilization, zygotic activation occurs t
World medicine November 30,2023
Scientists identify novel function of self-renewal factor of spermatogonial stem cells

Scientists identify novel function of self-renewal factor of spermatogonial stem cells

by Shinshu UniversityFGF2 expands RARG expressing subset of SSCs FGF2 facilitates RA action toward proper spermatogenesis. Credit: Seiji Takashima Ph.D., the Faculty of Textile Science and Technology
World medicine November 30,2023
Scientists identify novel function of self-renewal factor of spermatogonial stem cells

Scientists identify novel function of self-renewal factor of spermatogonial stem cells

by Shinshu UniversityFGF2 expands RARG expressing subset of SSCs FGF2 facilitates RA action toward proper spermatogenesis. Credit: Seiji Takashima Ph.D., the Faculty of Textile Science and Technology
World medicine November 30,2023
Improving the efficacy of cancer immunotherapy with modified CAR-T cells

Improving the efficacy of cancer immunotherapy with modified CAR-T cells

byUniversity of FreiburgCARs containing the CD3δ/ε/γ ICD are functional.a, Scheme depicting the ICD of all CD3 chains used in this study and the localization of the cysteines driving CAR d
World medicine November 30,2023
Improving the efficacy of cancer immunotherapy with modified CAR-T cells

Improving the efficacy of cancer immunotherapy with modified CAR-T cells

byUniversity of FreiburgCARs containing the CD3δ/ε/γ ICD are functional.a, Scheme depicting the ICD of all CD3 chains used in this study and the localization of the cysteines driving CAR d
World medicine November 30,2023
Landmark study signals shift in thinking about stem cell differentiation

Landmark study signals shift in thinking about stem cell differentiation

by Zachary Boehm,Florida State UniversityDavid M. Gilbert, the J. Herbert Taylor Distinguished Professor of Molecular Biology. Credit: FSU Photography ServicesA pioneering new study led by Flori
World medicine November 30,2023
Landmark study signals shift in thinking about stem cell differentiation

Landmark study signals shift in thinking about stem cell differentiation

by Zachary Boehm,Florida State UniversityDavid M. Gilbert, the J. Herbert Taylor Distinguished Professor of Molecular Biology. Credit: FSU Photography ServicesA pioneering new study led by Flori
World medicine November 30,2023
Infertility risk perception increased in survivors of adolescent and young adult cancer

Infertility risk perception increased in survivors of adolescent and young adult cancer

by Elana GotkineSurvivors of adolescent and young adult cancer have higher rates of perceiving increased infertility risk but frequently overestimate or underestimate their risk, according to a study
World medicine November 30,2023
Infertility risk perception increased in survivors of adolescent and young adult cancer

Infertility risk perception increased in survivors of adolescent and young adult cancer

by Elana GotkineSurvivors of adolescent and young adult cancer have higher rates of perceiving increased infertility risk but frequently overestimate or underestimate their risk, according to a study
World medicine November 30,2023
Colorectal cancer: Aspirin found to activate protective genes

Colorectal cancer: Aspirin found to activate protective genes

byLudwig Maximilian University of MunichSalicylate suppresses viability and proliferation of CRC cells independent of p53.ACell viability of HCT116 cells was determined by MTT assay
World medicine November 30,2023
Colorectal cancer: Aspirin found to activate protective genes

Colorectal cancer: Aspirin found to activate protective genes

byLudwig Maximilian University of MunichSalicylate suppresses viability and proliferation of CRC cells independent of p53.ACell viability of HCT116 cells was determined by MTT assay
World medicine November 30,2023
A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells

A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells

byWiley Credit: WileyKilling malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. Scientists from the UK have now synthesized a copper-conta
World medicine November 30,2023
A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells

A metallopeptide targets and disrupts mitochondrial function in breast cancer stem cells

byWiley Credit: WileyKilling malignant mitochondria is one of the most promising approaches in the development of new anticancer drugs. Scientists from the UK have now synthesized a copper-conta
World medicine November 30,2023
Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation

Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation

byHelmholtz Zentrum MünchenActivation of the Wnt/PCP signaling pathway (shown in green) in intestinal stem cells primes their fate towards the Paneth and enteroendocrine lineage. Credit: Helmhol
World medicine November 30,2023
Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation

Uncovering basic mechanisms of intestinal stem cell self-renewal and differentiation

byHelmholtz Zentrum MünchenActivation of the Wnt/PCP signaling pathway (shown in green) in intestinal stem cells primes their fate towards the Paneth and enteroendocrine lineage. Credit: Helmhol
World medicine November 30,2023
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