Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Updated on: December 25,2023 10

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Updated on:December 25,2023 10

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on: December 25,2023 10

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on:December 25,2023 10

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis

Updated on: November 07,2024 0

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis

Updated on:November 07,2024 0

An anticancer drug opens a new path for the treatment of Parkinson's

by Spanish National Research CouncilGraphical abstract. Credit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2024.01.007Once they enter the body, drugs, apart from carrying out

Updated on: May 21,2024 3

An anticancer drug opens a new path for the treatment of Parkinson's

by Spanish National Research CouncilGraphical abstract. Credit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2024.01.007Once they enter the body, drugs, apart from carrying out

Updated on:May 21,2024 3

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on: February 20,2024 20

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on:February 20,2024 20

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1

Updated on: July 09,2024 0

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1

Updated on:July 09,2024 0

Study shows clinical benefit of a new way of treating advanced ER+ breast cancer

by University of LiverpoolCredit: Unsplash/CC0 Public DomainA research paper published today inThe Lancet Oncologydemonstrates that the drug enobosarm, a selective androgen receptor m

Updated on: May 26,2024 3

Study shows clinical benefit of a new way of treating advanced ER+ breast cancer

by University of LiverpoolCredit: Unsplash/CC0 Public DomainA research paper published today inThe Lancet Oncologydemonstrates that the drug enobosarm, a selective androgen receptor m

Updated on:May 26,2024 3

A novel pill to treat bleeding from uterine fibroids aims for FDA approval

by Marie McCulloughCredit: CC0 Public DomainFor millions of premenopausal women, uterine fibroids turn their monthly periods into virtual hemorrhages.A new drug called elagolix cut blood loss by half

Updated on: May 10,2024 4

A novel pill to treat bleeding from uterine fibroids aims for FDA approval

by Marie McCulloughCredit: CC0 Public DomainFor millions of premenopausal women, uterine fibroids turn their monthly periods into virtual hemorrhages.A new drug called elagolix cut blood loss by half

Updated on:May 10,2024 4

Patient-derived Organoids: Revolutionizing Cancer Research and Treatment

Updated on: November 14,2024 0

Patient-derived Organoids: Revolutionizing Cancer Research and Treatment

Updated on:November 14,2024 0

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on: January 10,2024 9

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on:January 10,2024 9

Endometrial cancer: New insights into a deadly disparity

byMemorial Sloan Kettering Cancer CenterCredit: Pixabay/CC0 Public DomainEndometrial cancer—which develops in the lining of the uterus (womb) and is sometimes called uterine cancer—is on the ris

Updated on: December 28,2023 6

Endometrial cancer: New insights into a deadly disparity

byMemorial Sloan Kettering Cancer CenterCredit: Pixabay/CC0 Public DomainEndometrial cancer—which develops in the lining of the uterus (womb) and is sometimes called uterine cancer—is on the ris

Updated on:December 28,2023 6

Management of refractory or relapsed classic Hodgkin lymphoma in Brazil

by Impact Journals LLCHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Anew review papertitled "Current perspect

Updated on: December 28,2023 15

Management of refractory or relapsed classic Hodgkin lymphoma in Brazil

by Impact Journals LLCHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Anew review papertitled "Current perspect

Updated on:December 28,2023 15