How cellular plasticity drives cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainAbout 90% of deaths from cancer are a result of metastasis—that is, from cancer's ability to spread from

Updated on: April 28,2024

How cellular plasticity drives cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainAbout 90% of deaths from cancer are a result of metastasis—that is, from cancer's ability to spread from

Updated on:April 28,2024

Brain tumor organoids may be key to time-sensitive treatments for glioblastomas

byPerelman School of Medicine at the University of PennsylvaniaGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Lab-grown brain organoids developed from a patient's own glioblas

Updated on: December 22,2023

Brain tumor organoids may be key to time-sensitive treatments for glioblastomas

byPerelman School of Medicine at the University of PennsylvaniaGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Lab-grown brain organoids developed from a patient's own glioblas

Updated on:December 22,2023

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on: April 18,2024

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on:April 18,2024

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on: December 26,2023

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on:December 26,2023

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on: December 24,2023

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on:December 24,2023

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on: January 26,2024

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on:January 26,2024

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on: January 04,2024

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on:January 04,2024

A new way to stop cancer cells from killing their healthy neighbors

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainOne of the reasons cancer cells are so robust against the body's natural defenses is that they are in fact human cells, and as such t

Updated on: May 17,2024

A new way to stop cancer cells from killing their healthy neighbors

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainOne of the reasons cancer cells are so robust against the body's natural defenses is that they are in fact human cells, and as such t

Updated on:May 17,2024

In preclinical studies, team identifies potential therapy for metastatic colon cancer

by Weill Cornell Medical CollegeMultiplex immunofluorescence image of hyaluronan-rich human colorectal cancer. Highly aggressive tumoral cells (turquoise and magenta) are negative for both aPKCs

Updated on: February 24,2024

In preclinical studies, team identifies potential therapy for metastatic colon cancer

by Weill Cornell Medical CollegeMultiplex immunofluorescence image of hyaluronan-rich human colorectal cancer. Highly aggressive tumoral cells (turquoise and magenta) are negative for both aPKCs

Updated on:February 24,2024

Testosterone is an ally of macrophages in the battle against adrenal cancers

byCNRSMacrophages attacking adrenal tumor in male mouse. Credit: © Julie Olabe CNRS/GReDWhy are cancers of the adrenal glands more common among women? Why are prognoses worse for them? A team of

Updated on: December 22,2023

Testosterone is an ally of macrophages in the battle against adrenal cancers

byCNRSMacrophages attacking adrenal tumor in male mouse. Credit: © Julie Olabe CNRS/GReDWhy are cancers of the adrenal glands more common among women? Why are prognoses worse for them? A team of

Updated on:December 22,2023

Identifying new potential in cancer-killing T cells

by Kate Ledger,Mayo ClinicGraphical illustration of a general role of ME1 in resilient CD8+T cells. Credit:Science Advances(2023). DOI: 10.1126/sciadv.adi2414When Joanina Gicob

Updated on: January 25,2024

Identifying new potential in cancer-killing T cells

by Kate Ledger,Mayo ClinicGraphical illustration of a general role of ME1 in resilient CD8+T cells. Credit:Science Advances(2023). DOI: 10.1126/sciadv.adi2414When Joanina Gicob

Updated on:January 25,2024

Photodynamic therapy offers promise for cancer treatment

by Marcia Kaye,University of Toronto MississaugaHuman colorectal cancer cells. Credit: National Cancer Institute/UnsplashWhile chemotherapy drugs can be lifesaving, they don't work for all p

Updated on: December 23,2023

Photodynamic therapy offers promise for cancer treatment

by Marcia Kaye,University of Toronto MississaugaHuman colorectal cancer cells. Credit: National Cancer Institute/UnsplashWhile chemotherapy drugs can be lifesaving, they don't work for all p

Updated on:December 23,2023