How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on: January 10,2024

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on:January 10,2024

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on: December 22,2023

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on:December 22,2023

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on: January 25,2024

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on:January 25,2024

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on: January 05,2024

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on:January 05,2024

Microproteins exclusively produced in liver tumors could lead to cancer vaccines

by IMIM (Hospital del Mar Medical Research Institute)Credit: Pixabay/CC0 Public DomainA study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra Universit

Updated on: July 11,2024

Microproteins exclusively produced in liver tumors could lead to cancer vaccines

by IMIM (Hospital del Mar Medical Research Institute)Credit: Pixabay/CC0 Public DomainA study led by the Hospital del Mar Research Institute, with Cima University of Navarra and Pompeu Fabra Universit

Updated on:July 11,2024

Research details adaptation tactics of pancreatic cancer

byUniversity of OklahomaPSCs support cancer cell growth by the secretion of acetate under acidosis. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01372-4Like alien invade

Updated on: April 28,2024

Research details adaptation tactics of pancreatic cancer

byUniversity of OklahomaPSCs support cancer cell growth by the secretion of acetate under acidosis. Credit:Nature Cell Biology(2024). DOI: 10.1038/s41556-024-01372-4Like alien invade

Updated on:April 28,2024

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on: December 26,2023

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on:December 26,2023

Diabetes medication class tied to lower risk of kidney stones

by Mass General BrighamCredit: Pixabay/CC0 Public DomainRates of kidney stones are on the rise in the United States and around the world. Type 2 diabetes is associated with increased risk of kidn

Updated on: May 26,2024

Diabetes medication class tied to lower risk of kidney stones

by Mass General BrighamCredit: Pixabay/CC0 Public DomainRates of kidney stones are on the rise in the United States and around the world. Type 2 diabetes is associated with increased risk of kidn

Updated on:May 26,2024

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on: December 25,2023

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on:December 25,2023

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on: December 22,2023

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on:December 22,2023

What are 'cancer vaccines,' and what similarities do they share with COVID vaccines?

by Sathana Dushyanthen,The ConversationCredit: AI-generated imageBarely a month goes by without headlines announcing yet another advancement in cancer vaccines.Just last month, the United States

Updated on: January 04,2024

What are 'cancer vaccines,' and what similarities do they share with COVID vaccines?

by Sathana Dushyanthen,The ConversationCredit: AI-generated imageBarely a month goes by without headlines announcing yet another advancement in cancer vaccines.Just last month, the United States

Updated on:January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024