Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on: December 26,2023

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Updated on:December 26,2023

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on: January 10,2024

How do we overcome treatment resistance in a sarcoma cancer with already limited treatment options?

by Elena Daviter-Nowell,Institute of Cancer ResearchHistopathology image of leiomyosarcoma. Credit:Wikimedia Commons, CC-BY-SA 4.0Leiomyosarcoma is a type of soft tissue sarcoma that is ha

Updated on:January 10,2024

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023

As another obesity-fighting drug takes center stage, a nutrition expert discusses weight loss

by Mandy Conrad,The ConversationCredit: Unsplash/CC0 Public DomainIf the buzz surrounding a medication could elevate it to celebrity status, thenZepboundis reaching Taylor Swift rank

Updated on: March 26,2024

As another obesity-fighting drug takes center stage, a nutrition expert discusses weight loss

by Mandy Conrad,The ConversationCredit: Unsplash/CC0 Public DomainIf the buzz surrounding a medication could elevate it to celebrity status, thenZepboundis reaching Taylor Swift rank

Updated on:March 26,2024

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on: December 22,2023

Adjuvant nivolumab + ipilimumab lacks efficacy for localized renal cell carcinoma

Disease-free survival (DFS) does not differ with adjuvant nivolumab plus ipilimumab (NIVO+IPI) compared with placebo in patients with localized renal cell carcinoma (RCC) at high risk for postnephrect

Updated on:December 22,2023

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on: December 02,2024

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on:December 02,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024

The inaugural Sony-Nature Tech Women Award announced, with four winners

Updated on: February 17,2025

The inaugural Sony-Nature Tech Women Award announced, with four winners

Updated on:February 17,2025

Racial disparities in lung cancer start with research

by Melba NewsomeCredit: Pixabay/CC0 Public DomainDuring a routine visit to the Good Samaritan Clinic in Morganton, North Carolina, in 2018, Herbert Buff casually mentioned that he sometimes had troubl

Updated on: December 22,2023

Racial disparities in lung cancer start with research

by Melba NewsomeCredit: Pixabay/CC0 Public DomainDuring a routine visit to the Good Samaritan Clinic in Morganton, North Carolina, in 2018, Herbert Buff casually mentioned that he sometimes had troubl

Updated on:December 22,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on: December 26,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on:December 26,2023

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on: December 18,2023

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on:December 18,2023

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on: March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Updated on:March 27,2024