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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Fewer cases of melanoma observed among people taking vitamin D supplements

Fewer cases of melanoma observed among people taking vitamin D supplements

byUniversity of Eastern FinlandCredit: Unsplash/CC0 Public DomainFewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. Peopl

Fewer cases of melanoma observed among people taking vitamin D supplements

byUniversity of Eastern FinlandCredit: Unsplash/CC0 Public DomainFewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. Peopl
Surgery first for colon cancer? Not so fast, according to new study

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li
Mounjaro beats Ozempic for weight loss in early trial

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp

Mounjaro beats Ozempic for weight loss in early trial

by Robin FosterThe diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozemp
Protein spheres protect the genome of cancer cells

Protein spheres protect the genome of cancer cells

byUniversity of WürzburgMYC proteins are colored green in this figure. In normally growing cells, they are homogeneously distributed in the cell nucleus (left). In diverse stress situations, as

Protein spheres protect the genome of cancer cells

byUniversity of WürzburgMYC proteins are colored green in this figure. In normally growing cells, they are homogeneously distributed in the cell nucleus (left). In diverse stress situations, as
Understanding early effects of psoriasis drug offers potential for personalized treatment

Understanding early effects of psoriasis drug offers potential for personalized treatment

by King's College LondonDiagram showing the early effects of therapeutic IL-23 inhibition. Left: in lesional psoriasis skin, IL-23 drives the differentiation of T17 cells. Right: following IL

Understanding early effects of psoriasis drug offers potential for personalized treatment

by King's College LondonDiagram showing the early effects of therapeutic IL-23 inhibition. Left: in lesional psoriasis skin, IL-23 drives the differentiation of T17 cells. Right: following IL
Genomic assay may predict long-term prognosis in premenopausal patients with HR-positive early-stage breast cancer

Genomic assay may predict long-term prognosis in premenopausal patients with HR-positive early-stage breast cancer

byAmerican Association for Cancer ResearchThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in

Genomic assay may predict long-term prognosis in premenopausal patients with HR-positive early-stage breast cancer

byAmerican Association for Cancer ResearchThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in
Even moderate exercise linked to reduced mortality after breast cancer

Even moderate exercise linked to reduced mortality after breast cancer

by Elana GotkineEven moderate physical activity is associated with a reduced risk for mortality for breast cancer survivors, according to a study published online Nov. 17 inJAMA Network Open.Lie

Even moderate exercise linked to reduced mortality after breast cancer

by Elana GotkineEven moderate physical activity is associated with a reduced risk for mortality for breast cancer survivors, according to a study published online Nov. 17 inJAMA Network Open.Lie
Establishment of breast phyllodes tumor cell lines to facilitate future studies

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),

Establishment of breast phyllodes tumor cell lines to facilitate future studies

by Compuscript LtdCredit: CC0 Public DomainBreast phyllodes tumors (PTs) are biphasic, with epithelial and stromal components. Although the PT incidence is low (approximately 1% of all breast tumors),
Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of
Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri
Fighting racial bias in next-gen breast cancer screening

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a
Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to