Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on: January 28,2024

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on:January 28,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on: December 30,2023

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on:December 30,2023

Combination immunotherapy produces high response rate in early results of trial targeting high-risk follicular lymphoma

byUniversity of Miami Leonard M. Miller School of MedicineCancer cell during cell division. Credit: National Institutes of HealthResearchers conducting a Phase 2 clinical trial at Sylvester Comp

Updated on: January 26,2024

Combination immunotherapy produces high response rate in early results of trial targeting high-risk follicular lymphoma

byUniversity of Miami Leonard M. Miller School of MedicineCancer cell during cell division. Credit: National Institutes of HealthResearchers conducting a Phase 2 clinical trial at Sylvester Comp

Updated on:January 26,2024

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on: August 27,2024

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on:August 27,2024

Research raises hope for new therapies for chordoma, a rare bone cancer

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsChordoma is literally a one in a million cancer, with few effective treatment options. A new unde

Updated on: May 31,2024

Research raises hope for new therapies for chordoma, a rare bone cancer

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsChordoma is literally a one in a million cancer, with few effective treatment options. A new unde

Updated on:May 31,2024

Obstacles for breast cancer prevention in high-risk Black women

by Misti Crane,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainBlack women at high risk of breast cancer face a variety of obstacles that may keep them from care that could prevent ca

Updated on: December 22,2023

Obstacles for breast cancer prevention in high-risk Black women

by Misti Crane,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainBlack women at high risk of breast cancer face a variety of obstacles that may keep them from care that could prevent ca

Updated on:December 22,2023

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on: December 22,2023

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on:December 22,2023

Biomarker blood test confirms remission in patients with HPV+ oral cancer

byAmerican Society for Radiation OncologyA highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related

Updated on: December 18,2023

Biomarker blood test confirms remission in patients with HPV+ oral cancer

byAmerican Society for Radiation OncologyA highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related

Updated on:December 18,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Updated on: December 25,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Updated on:December 25,2023

Magnetic field patterns found to cause oncolysis via oxidative stress in glioma cells

by Thamarasee Jeewandara , Medical XpressCell culture stimulation setup, stimulation protocol and thermal imaging during sOMF stimulation to measure temperature changes. (A) Left—A schematic diagram o

Updated on: January 04,2024

Magnetic field patterns found to cause oncolysis via oxidative stress in glioma cells

by Thamarasee Jeewandara , Medical XpressCell culture stimulation setup, stimulation protocol and thermal imaging during sOMF stimulation to measure temperature changes. (A) Left—A schematic diagram o

Updated on:January 04,2024