Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on: December 30,2023 11

Massive drug search uncovers infinitesimal molecule that kills cancers while sparing immune cells

by Delthia Ricks , Medical XpressN6F11 suppresses the growth of human PDAC. (A) PANC1 cells were pretreated with DMSO or N6F11 (5 µM) for 12 hours. (B) MiaPACA2 cells were pretreated with DMSO or N6F1

Updated on:December 30,2023 11

Researchers propose a new treatment for brain metastasis based on immunotherapy

byThe Spanish National Cancer Research CentreCells around a brain metastasis in an animal model: several brain cells (astrocytes, white) surround an immune system cell (lymphocyte, green). Some

Updated on: October 24,2024 0

Researchers propose a new treatment for brain metastasis based on immunotherapy

byThe Spanish National Cancer Research CentreCells around a brain metastasis in an animal model: several brain cells (astrocytes, white) surround an immune system cell (lymphocyte, green). Some

Updated on:October 24,2024 0

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on: December 25,2023 6

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on:December 25,2023 6

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on: April 14,2024 15

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on:April 14,2024 15

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on: February 20,2024 20

Researchers target mutation that leads to pancreatic cancer

by Leslie Cantu,Medical University of South CarolinaCrystal structures of 12D5(K63S) in complex with KRAS(G12D)•GTPγS and with KRAS(G12D)•GDP. (A) A comparison of 12D5(K63S)–KRAS(G12D)•GTPγS (Le

Updated on:February 20,2024 20

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on: January 28,2024 16

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on:January 28,2024 16

Trends and hotspots in lung cancer surgery research reviewed over the last decade

by Health Data ScienceTrends of (a) annual scholarly outputs and (b) average field citation ratios in the world and top five countries in the field of lung cancer surgery, 2012-2021, and association b

Updated on: December 25,2023 8

Trends and hotspots in lung cancer surgery research reviewed over the last decade

by Health Data ScienceTrends of (a) annual scholarly outputs and (b) average field citation ratios in the world and top five countries in the field of lung cancer surgery, 2012-2021, and association b

Updated on:December 25,2023 8

Going for a walk wasn't really a thing 300 years ago—the Victorians turned it into a popular pastime

by Lauren Nichola Colley,The ConversationCredit: Pixabay/CC0 Public DomainGoing for a walk is always a good idea. Perhaps, if you are lucky enough, this might be a hike along ragged cliffs or tr

Updated on: March 22,2024 13

Going for a walk wasn't really a thing 300 years ago—the Victorians turned it into a popular pastime

by Lauren Nichola Colley,The ConversationCredit: Pixabay/CC0 Public DomainGoing for a walk is always a good idea. Perhaps, if you are lucky enough, this might be a hike along ragged cliffs or tr

Updated on:March 22,2024 13

Two new studies show how bacteria could help tumors progress and resist treatment

byFred Hutchinson Cancer Research CenterCredit: CC0 Public DomainTwo new studies from researchers at Fred Hutchinson Cancer Center in Seattle reveal how bacteria infiltrate tumors and could be h

Updated on: December 28,2023 10

Two new studies show how bacteria could help tumors progress and resist treatment

byFred Hutchinson Cancer Research CenterCredit: CC0 Public DomainTwo new studies from researchers at Fred Hutchinson Cancer Center in Seattle reveal how bacteria infiltrate tumors and could be h

Updated on:December 28,2023 10

CAR-T cell researchers optimistic about future of treating blood cancers

by Kelley Luckstein,Mayo ClinicCredit: AI-generated imageSurvival outcomes using chimeric antigen receptor-T cell therapy (CAR-T cell therapy) continue to be impressive for patients with some bl

Updated on: April 09,2024 14

CAR-T cell researchers optimistic about future of treating blood cancers

by Kelley Luckstein,Mayo ClinicCredit: AI-generated imageSurvival outcomes using chimeric antigen receptor-T cell therapy (CAR-T cell therapy) continue to be impressive for patients with some bl

Updated on:April 09,2024 14

Sandalwood oil by-product found to prevent prostate cancer development in mice

by Florida Atlantic UniversityGraphical abstract. Credit:Phytomedicine Plus(2024). DOI: 10.1016/j.phyplu.2024.100523Extracted from the core of sandalwood trees (santalum album tree),

Updated on: May 07,2024 11

Sandalwood oil by-product found to prevent prostate cancer development in mice

by Florida Atlantic UniversityGraphical abstract. Credit:Phytomedicine Plus(2024). DOI: 10.1016/j.phyplu.2024.100523Extracted from the core of sandalwood trees (santalum album tree),

Updated on:May 07,2024 11

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on: March 14,2024 16

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on:March 14,2024 16