Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on: December 30,2023

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on:December 30,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on: December 25,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on:December 25,2023

Thousands of cancer patients to trial personalised vaccines in England | BBC News

Updated on: August 28,2024

Thousands of cancer patients to trial personalised vaccines in England | BBC News

Updated on:August 28,2024

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on: June 14,2025

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on:June 14,2025

Lung cancer study finds new target for treatment resistance after EGFR inhibitors

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed

Updated on: December 22,2023

Lung cancer study finds new target for treatment resistance after EGFR inhibitors

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed

Updated on:December 22,2023

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on: January 02,2024

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on:January 02,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on: September 15,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on:September 15,2024

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on: December 25,2023

New method for early detection of multi-cancers based on human metabolism

bySwedish Research CouncilValidation of the pruned combined free GAGome MCED score. (A) Validation study subject flow (see also SI Appendix, Fig. S17). (B) Pruned combined free GAGome MCED score

Updated on:December 25,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on: December 20,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on:December 20,2023

Access to high-cost targeted treatments varies for lung cancer

(HealthDay)—Not all patients have access to new, high-cost lung cancer drugs, according to a study recently published in theJournal of the National Cancer Institute.Cathy J. Bradley, Ph.D., from

Updated on: December 22,2023

Access to high-cost targeted treatments varies for lung cancer

(HealthDay)—Not all patients have access to new, high-cost lung cancer drugs, according to a study recently published in theJournal of the National Cancer Institute.Cathy J. Bradley, Ph.D., from

Updated on:December 22,2023

Obstacles for breast cancer prevention in high-risk Black women

by Misti Crane,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainBlack women at high risk of breast cancer face a variety of obstacles that may keep them from care that could prevent ca

Updated on: December 22,2023

Obstacles for breast cancer prevention in high-risk Black women

by Misti Crane,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainBlack women at high risk of breast cancer face a variety of obstacles that may keep them from care that could prevent ca

Updated on:December 22,2023