Team finds key to common cancer pathway

by Terry Devitt,University of Wisconsin-MadisonThe molecular pathway for the protein p53, commonly associated with many cancers, is illuminated in this micrograph. The p53 - PIP2 complex is show

Updated on: May 27,2024

Team finds key to common cancer pathway

by Terry Devitt,University of Wisconsin-MadisonThe molecular pathway for the protein p53, commonly associated with many cancers, is illuminated in this micrograph. The p53 - PIP2 complex is show

Updated on:May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on: January 02,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on:January 02,2024

Children of parents with cancer history in US may be vulnerable to housing, food and financial hardship

by American Cancer SocietyCredit: Pixabay/CC0 Public DomainA new study by researchers at the American Cancer Society (ACS) found children of parents with a cancer history in the United States are

Updated on: January 30,2024

Children of parents with cancer history in US may be vulnerable to housing, food and financial hardship

by American Cancer SocietyCredit: Pixabay/CC0 Public DomainA new study by researchers at the American Cancer Society (ACS) found children of parents with a cancer history in the United States are

Updated on:January 30,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

Tumors grown in the lab provide insights on rare prostate cancer

by Weill Cornell Medical CollegeImage of prostate cancer organoids demonstrating expression of synaptophysin (stained in green), a marker protein for neuroendocrine cells. Credit: Beltran LabGrow

Updated on: April 22,2024

Tumors grown in the lab provide insights on rare prostate cancer

by Weill Cornell Medical CollegeImage of prostate cancer organoids demonstrating expression of synaptophysin (stained in green), a marker protein for neuroendocrine cells. Credit: Beltran LabGrow

Updated on:April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on: April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on:April 22,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on: January 30,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on:January 30,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on: January 30,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on:January 30,2024

Novel checklist for 'quality of life' to take cancer clinical trials to the next level

byEuropean Society for Medical OncologyCredit:Annals of Oncology(2022). DOI: 10.1016/j.annonc.2022.12.004The European Society for Medical Oncology (ESMO) has developed a quality of l

Updated on: January 11,2024

Novel checklist for 'quality of life' to take cancer clinical trials to the next level

byEuropean Society for Medical OncologyCredit:Annals of Oncology(2022). DOI: 10.1016/j.annonc.2022.12.004The European Society for Medical Oncology (ESMO) has developed a quality of l

Updated on:January 11,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on: February 20,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on:February 20,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024