Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

Researchers discover key genetic mutations in bowel cancer cells that lead to resistance to WRN inhibitors

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainResearchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibit

Updated on: November 09,2024

Researchers discover key genetic mutations in bowel cancer cells that lead to resistance to WRN inhibitors

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainResearchers have discovered key mutations in certain cancer cells that make them resistant to WRN inhibit

Updated on:November 09,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on: February 19,2024

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on:February 19,2024

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer

Updated on: March 27,2024

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer

Updated on:March 27,2024

Staying safe in the sun — a dermatologist helps separate facts from hype

by University of California, San FranciscoCredit: Elena ZhukovaSkin cancer is the number-one cancer diagnosis in the United States – it's more common than breast, prostate, and lung cancers c

Updated on: April 20,2024

Staying safe in the sun — a dermatologist helps separate facts from hype

by University of California, San FranciscoCredit: Elena ZhukovaSkin cancer is the number-one cancer diagnosis in the United States – it's more common than breast, prostate, and lung cancers c

Updated on:April 20,2024

Researchers discover a new cancer-driving mutation in 'dark matter' of the cancer genome

by Ontario Institute for Cancer ResearchCredit: CC0 Public DomainAn Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome,

Updated on: June 04,2024

Researchers discover a new cancer-driving mutation in 'dark matter' of the cancer genome

by Ontario Institute for Cancer ResearchCredit: CC0 Public DomainAn Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome,

Updated on:June 04,2024

Depression affects one-third of lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityCredit: CC0 Public DomainAbout one-third of patients newly diagnosed with the most common form of lung cancer have moderate to severe symptoms of depre

Updated on: May 11,2024

Depression affects one-third of lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityCredit: CC0 Public DomainAbout one-third of patients newly diagnosed with the most common form of lung cancer have moderate to severe symptoms of depre

Updated on:May 11,2024

Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on: January 22,2024

Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on:January 22,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on: February 18,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on:February 18,2024

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on: August 03,2024

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on:August 03,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on: March 30,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on:March 30,2024

Treating tumors with engineered dendritic cells

by Ecole Polytechnique Federale de LausanneCerebral tumor (glioma) of a mouse. Credit: EPFL / Michele De Palma—CC-BY-SA 4.0Cancer biologists at EPFL, UNIGE, and the German Cancer Research Center

Updated on: May 11,2024

Treating tumors with engineered dendritic cells

by Ecole Polytechnique Federale de LausanneCerebral tumor (glioma) of a mouse. Credit: EPFL / Michele De Palma—CC-BY-SA 4.0Cancer biologists at EPFL, UNIGE, and the German Cancer Research Center

Updated on:May 11,2024