Sugar molecules as a target in cancer therapy

byUniversity of BaselTherapeutic desialylation repolarizes tumor-associated macrophages (TAMs). (A) Pathway enrichment analysis performed on all macrophages between treatment conditions. UT, unt

Updated on: January 07,2024

Sugar molecules as a target in cancer therapy

byUniversity of BaselTherapeutic desialylation repolarizes tumor-associated macrophages (TAMs). (A) Pathway enrichment analysis performed on all macrophages between treatment conditions. UT, unt

Updated on:January 07,2024

Appendiceal cancer gets its own preclinical model

byUniversity of California - San DiegoConfocal image of a living tissue slice derived from a patient tumor with metastatic appendiceal cancer (mucinous carcinomatosis peritonei). Immunofluoresce

Updated on: December 28,2023

Appendiceal cancer gets its own preclinical model

byUniversity of California - San DiegoConfocal image of a living tissue slice derived from a patient tumor with metastatic appendiceal cancer (mucinous carcinomatosis peritonei). Immunofluoresce

Updated on:December 28,2023

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo

Updated on: January 04,2024

Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainOver the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment fo

Updated on:January 04,2024

Experimental ovarian cancer diagnostic could lead to new precision oncology approach

byFred Hutchinson Cancer CenterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (

Updated on: January 04,2024

Experimental ovarian cancer diagnostic could lead to new precision oncology approach

byFred Hutchinson Cancer CenterIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium (

Updated on:January 04,2024

Attenuation of cancer proliferation by suppression of glypican-1

by Impact Journals LLCOverexpression of GPC1 increases proliferation of T24 cells. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28388A new research paper titled "Attenuation of c

Updated on: February 01,2024

Attenuation of cancer proliferation by suppression of glypican-1

by Impact Journals LLCOverexpression of GPC1 increases proliferation of T24 cells. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28388A new research paper titled "Attenuation of c

Updated on:February 01,2024

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on: April 01,2024

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on:April 01,2024

Researcher patents 'roach motel' for cancer

by Louisa Kellie,University of Texas at ArlingtonA cancer trap. Credit: UTAThe University of Texas at Arlington has successfully patented in Europe an implantable medical device that attracts an

Updated on: June 04,2024

Researcher patents 'roach motel' for cancer

by Louisa Kellie,University of Texas at ArlingtonA cancer trap. Credit: UTAThe University of Texas at Arlington has successfully patented in Europe an implantable medical device that attracts an

Updated on:June 04,2024

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on: January 13,2024

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on:January 13,2024

Researchers identify effective drug combination against uveal melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Uveal mela

Updated on: June 08,2024

Researchers identify effective drug combination against uveal melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Uveal mela

Updated on:June 08,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on: May 20,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on:May 20,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on: January 12,2024

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

Updated on:January 12,2024

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on: January 30,2024

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on:January 30,2024