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Medicial Breakthroughs
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Gene therapy advances as scientists guide jumping DNA to target faulty genes

Gene therapy advances as scientists guide jumping DNA to target faulty genes

by Matthew Campbell,University of Hawaii at ManoaIdentification of Exc+Int⁻ DNA-binding domain mutants to minimize off-target integration. Credit:Nucleic Acids Research(2025). DOI: 10.1093/nar/gkaf131

Gene therapy advances as scientists guide jumping DNA to target faulty genes

by Matthew Campbell,University of Hawaii at ManoaIdentification of Exc+Int⁻ DNA-binding domain mutants to minimize off-target integration. Credit:Nucleic Acids Research(2025). DOI: 10.1093/nar/gkaf131
Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics

Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics

byUniversity of California, San FranciscoPerformance of FABP4, GPT-4 and integrated LRTI diagnostic classifiers in the derivation and validation cohorts. Credit:Nature Communications(2025). DOI: 10.10

Using both genetic information and AI to diagnose pneumonia could curb the overuse of antibiotics

byUniversity of California, San FranciscoPerformance of FABP4, GPT-4 and integrated LRTI diagnostic classifiers in the derivation and validation cohorts. Credit:Nature Communications(2025). DOI: 10.10
RNA steps outside the cell to help guide immune responses, study suggests

RNA steps outside the cell to help guide immune responses, study suggests

byUtrecht UniversitySchematic model showing how cell-surface RNA (csRNA) is anchored to the cell membrane via heparan sulfate and RNA-binding proteins, and how it can help bring immune receptors (such

RNA steps outside the cell to help guide immune responses, study suggests

byUtrecht UniversitySchematic model showing how cell-surface RNA (csRNA) is anchored to the cell membrane via heparan sulfate and RNA-binding proteins, and how it can help bring immune receptors (such
Breakdown products from 'eco-friendly' plastics impede fetal development in mice, study shows

Breakdown products from 'eco-friendly' plastics impede fetal development in mice, study shows

byPublic Library of SciencePLA plastic breakdown product oligomeric nanoplastics can penetrate the placental barrier and reach the fetus. Credit: Dr. Jia Lv (CC-BY 4.0, creativecommons.org/licenses/by

Breakdown products from 'eco-friendly' plastics impede fetal development in mice, study shows

byPublic Library of SciencePLA plastic breakdown product oligomeric nanoplastics can penetrate the placental barrier and reach the fetus. Credit: Dr. Jia Lv (CC-BY 4.0, creativecommons.org/licenses/by
Genetically modified marmosets as a model for human deafness provide a foundation for future gene therapies

Genetically modified marmosets as a model for human deafness provide a foundation for future gene therapies

by Susanne Diederich,The German Primate CenterMyrabello, a genetically modified marmoset. Credit: Katharina DiederichWhy are some people unable to hear from birth, even though their inner ear appears

Genetically modified marmosets as a model for human deafness provide a foundation for future gene therapies

by Susanne Diederich,The German Primate CenterMyrabello, a genetically modified marmoset. Credit: Katharina DiederichWhy are some people unable to hear from birth, even though their inner ear appears
How the brain fine-tunes fear as threats fade

How the brain fine-tunes fear as threats fade

byTulane UniversityCredit: Pixabay/CC0 Public DomainResearchers at Tulane University have identified brain circuits that help determine how fear responses change as perceived threats diminish, offerin

How the brain fine-tunes fear as threats fade

byTulane UniversityCredit: Pixabay/CC0 Public DomainResearchers at Tulane University have identified brain circuits that help determine how fear responses change as perceived threats diminish, offerin
Neurons use physical signals, not electricity, to stabilize communication

Neurons use physical signals, not electricity, to stabilize communication

byUniversity of Southern CaliforniaCredit: Pixabay/CC0 Public DomainEvery movement you make and every memory you form depends on precise communication between neurons. When that communication is disru

Neurons use physical signals, not electricity, to stabilize communication

byUniversity of Southern CaliforniaCredit: Pixabay/CC0 Public DomainEvery movement you make and every memory you form depends on precise communication between neurons. When that communication is disru
The body's internal clock can be determined from a hair sample

The body's internal clock can be determined from a hair sample

byCharité - Universitätsmedizin BerlinA single hair sample is sufficient to determine a person's internal clock rhythm. Credit: Charité | Bert MaierA research team at Charité–Universitätsmedizin B

The body's internal clock can be determined from a hair sample

byCharité - Universitätsmedizin BerlinA single hair sample is sufficient to determine a person's internal clock rhythm. Credit: Charité | Bert MaierA research team at Charité–Universitätsmedizin B
Clinical trial suggests knowing HIV 'viral load' doesn't improve number of patients seeking needed care

Clinical trial suggests knowing HIV 'viral load' doesn't improve number of patients seeking needed care

by Michael E. Newman,Johns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainAccording to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are ap

Clinical trial suggests knowing HIV 'viral load' doesn't improve number of patients seeking needed care

by Michael E. Newman,Johns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainAccording to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are ap
Gene therapy for hereditary spastic paraplegia hits proof-of-principle milestone

Gene therapy for hereditary spastic paraplegia hits proof-of-principle milestone

by Greg Richter,Drexel UniversityCredit: Unsplash/CC0 Public DomainThere is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Me

Gene therapy for hereditary spastic paraplegia hits proof-of-principle milestone

by Greg Richter,Drexel UniversityCredit: Unsplash/CC0 Public DomainThere is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Me