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Breakthroughs
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Human cells building 'molecular highways' captured for first time

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the
'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,
A step closer to treatment for severe bacterial infections and sepsis

A step closer to treatment for severe bacterial infections and sepsis

JANUARY 10, 2024byLund UniversityThe illustration depicts how the researchers' peptide treatment (pink) binds to both receptors that can detect bacterial substances (green) and to bacterial

A step closer to treatment for severe bacterial infections and sepsis

JANUARY 10, 2024byLund UniversityThe illustration depicts how the researchers' peptide treatment (pink) binds to both receptors that can detect bacterial substances (green) and to bacterial
Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI
Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur
Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they
New tool improves the search for genes that cause diseases

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch
Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb
Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r
HIV: Early treatment is one key to remission

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-
Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide