Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024 0

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on: October 22,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on:October 22,2024 0

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers

Updated on: December 04,2024 0

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers

Updated on:December 04,2024 0

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on: March 30,2024 10

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on:March 30,2024 10

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on: May 08,2024 5

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on:May 08,2024 5

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Updated on: March 14,2024 15

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Updated on:March 14,2024 15

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on: March 25,2024 5

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on:March 25,2024 5

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va

Updated on: March 15,2024 4

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va

Updated on:March 15,2024 4

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

Updated on: March 25,2024 3

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

Updated on:March 25,2024 3

Better MRI videos thanks to new machine learning method

by Philipp Jarke,Graz University of TechnologyShort-axis section through the heart: The simple MRI image reconstruction method "Gridding" (left), "RT-NLINV" method developed

Updated on: October 09,2024 0

Better MRI videos thanks to new machine learning method

by Philipp Jarke,Graz University of TechnologyShort-axis section through the heart: The simple MRI image reconstruction method "Gridding" (left), "RT-NLINV" method developed

Updated on:October 09,2024 0

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each

Updated on: April 06,2024 0

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each

Updated on:April 06,2024 0