Gene therapy could fight leukemia in Down syndrome children

by FreshscienceCredit: Pixabay/CC0 Public DomainChildren with Down syndrome (DS) are 20 times more likely to develop leukemia. Not only are they more likely to develop the disease, they have higher ra

Pediatrics December 25,2023

Gene therapy could fight leukemia in Down syndrome children

by FreshscienceCredit: Pixabay/CC0 Public DomainChildren with Down syndrome (DS) are 20 times more likely to develop leukemia. Not only are they more likely to develop the disease, they have higher ra

Pediatrics December 25,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Oncology December 25,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Oncology December 25,2023

Genetic test could guide use of cancer chemotherapy

by Ellie Cawthera,Imperial College LondonDiscovery ofKRASG12mutation status as potential biomarker of outcome of FTD/TPI treatment in mCRC.a, Dot plot showing the associations

Oncology December 25,2023

Genetic test could guide use of cancer chemotherapy

by Ellie Cawthera,Imperial College LondonDiscovery ofKRASG12mutation status as potential biomarker of outcome of FTD/TPI treatment in mCRC.a, Dot plot showing the associations

Oncology December 25,2023

Genetic tests create treatment opportunities and confusion for breast cancer patients

by Michelle AndrewsCredit: Pixabay/CC0 Public DomainThe past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been diagnosed with breast c

Oncology December 25,2023

Genetic tests create treatment opportunities and confusion for breast cancer patients

by Michelle AndrewsCredit: Pixabay/CC0 Public DomainThe past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been diagnosed with breast c

Oncology December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Oncology December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Oncology December 25,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Oncology December 25,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Oncology December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Oncology December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Oncology December 25,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Oncology December 25,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Oncology December 25,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Oncology December 25,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Oncology December 25,2023

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and

Breakthroughs December 25,2023

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and

Breakthroughs December 25,2023