Fiber, genes and the gut microbiome: Study reveals possible triggers for inflammatory bowel disease

byUniversity of MichiganGraphical abstract. Credit:Cell Host & Microbe(2024). DOI: 10.1016/j.chom.2024.03.001Abdominal pain, diarrhea, weight loss—these and the other symptoms of

Gastroenterology March 27,2024

Fiber, genes and the gut microbiome: Study reveals possible triggers for inflammatory bowel disease

byUniversity of MichiganGraphical abstract. Credit:Cell Host & Microbe(2024). DOI: 10.1016/j.chom.2024.03.001Abdominal pain, diarrhea, weight loss—these and the other symptoms of

Gastroenterology March 27,2024

Oxidative stress in heart failure found to vary between males and females

byKarolinska InstitutetA summary of the proposed molecular mechanism. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46384-8Researchers from Karolinska Institutet, Astra

Cardiovascular Diseases March 27,2024

Oxidative stress in heart failure found to vary between males and females

byKarolinska InstitutetA summary of the proposed molecular mechanism. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46384-8Researchers from Karolinska Institutet, Astra

Cardiovascular Diseases March 27,2024

Researchers roll out a more accurate way to estimate genetic risks of disease

by Claire Hendershot,Broad Institute of MIT and HarvardPrediction accuracy and improvement across various types of traits in the European and South Asian ancestry. Credit:Cell Genomics&nbs

Breakthroughs March 27,2024

Researchers roll out a more accurate way to estimate genetic risks of disease

by Claire Hendershot,Broad Institute of MIT and HarvardPrediction accuracy and improvement across various types of traits in the European and South Asian ancestry. Credit:Cell Genomics&nbs

Breakthroughs March 27,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Breakthroughs March 27,2024

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Breakthroughs March 27,2024

ALG6 acts as a modifier gene in the inherited genetic eye disease retinitis pigmentosa 59

by Jeff Hansen,University of Alabama at BirminghamRepresentative chromatograms for each potential modifier gene. DNA from each patient sample was PCR-amplified at all five modifier sites and pur

Ophthalmology March 27,2024

ALG6 acts as a modifier gene in the inherited genetic eye disease retinitis pigmentosa 59

by Jeff Hansen,University of Alabama at BirminghamRepresentative chromatograms for each potential modifier gene. DNA from each patient sample was PCR-amplified at all five modifier sites and pur

Ophthalmology March 27,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Neurology March 27,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Neurology March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Oncology March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Oncology March 27,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Breakthroughs March 27,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Breakthroughs March 27,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Orthopedics & Sports medicine March 27,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Orthopedics & Sports medicine March 27,2024

Shining a light on the genetic underpinnings of a rare disease impacting children

by David McFadden,University of OttawaSynopsis. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00082-0A team from the University of Ottawa's Faculty of Medicine has completed

Pediatrics March 27,2024

Shining a light on the genetic underpinnings of a rare disease impacting children

by David McFadden,University of OttawaSynopsis. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00082-0A team from the University of Ottawa's Faculty of Medicine has completed

Pediatrics March 27,2024