First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Neurology March 27,2024

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Neurology March 27,2024

Study with rodents identifies key genes for control of blood pressure and heart rate

by Maria Fernanda Ziegler,FAPESPComprehensive overview of genetic screening with automated meiotic mapping. (A) Founder animals (G1) were characterized by whole-exome sequencing to identify ENU-

Cardiovascular Diseases March 27,2024

Study with rodents identifies key genes for control of blood pressure and heart rate

by Maria Fernanda Ziegler,FAPESPComprehensive overview of genetic screening with automated meiotic mapping. (A) Founder animals (G1) were characterized by whole-exome sequencing to identify ENU-

Cardiovascular Diseases March 27,2024

Blood analysis predicts sepsis and organ failure in children

by University of QueenslandCredit: Karolina Grabowska from PexelsUniversity of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ f

Emergency Medicine & Critical Care March 27,2024

Blood analysis predicts sepsis and organ failure in children

by University of QueenslandCredit: Karolina Grabowska from PexelsUniversity of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ f

Emergency Medicine & Critical Care March 27,2024

Researchers identify protein sensor that plays a role in lung fibrosis

byWeill Cornell Medical CollegeIn normal human lung tissue (left), the SEL1L protein (tagged green) is prominent. The fibrotic lung tissue (right) is characterized by excess collagen (tagged red

Pulmonology March 27,2024

Researchers identify protein sensor that plays a role in lung fibrosis

byWeill Cornell Medical CollegeIn normal human lung tissue (left), the SEL1L protein (tagged green) is prominent. The fibrotic lung tissue (right) is characterized by excess collagen (tagged red

Pulmonology March 27,2024

Colorectal cancer gene implicated in broad range of solid tumors

by Amy Mone, Valerie Mehl,Johns Hopkins UniversityMUTYH-altered samples. (A) CONSORT diagram showing grouping of samples. Samples with somatic MUTYH alterations including pathogenic short varian

Oncology March 27,2024

Colorectal cancer gene implicated in broad range of solid tumors

by Amy Mone, Valerie Mehl,Johns Hopkins UniversityMUTYH-altered samples. (A) CONSORT diagram showing grouping of samples. Samples with somatic MUTYH alterations including pathogenic short varian

Oncology March 27,2024

Research suggests natural compound could be promising new alternative treatment for colon cancer

FEBRUARY 26, 2024byUniversity of PortsmouthSchisandrin B inhibits the proliferation of human colon cancer cells. Credit:ACS Pharmacology & Translational Science(2024). DOI: 10.10

Oncology March 27,2024

Research suggests natural compound could be promising new alternative treatment for colon cancer

FEBRUARY 26, 2024byUniversity of PortsmouthSchisandrin B inhibits the proliferation of human colon cancer cells. Credit:ACS Pharmacology & Translational Science(2024). DOI: 10.10

Oncology March 27,2024

Hepatitis C virus infection: Research team discovers that a protein has an unexpected proviral effect

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelThe expression of GBP1 is increased in HCV replicating cells. Credit:PLOS Pathogens&nbsp

Hepatobiliary&Pancreas Surgery March 27,2024

Hepatitis C virus infection: Research team discovers that a protein has an unexpected proviral effect

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelThe expression of GBP1 is increased in HCV replicating cells. Credit:PLOS Pathogens&nbsp

Hepatobiliary&Pancreas Surgery March 27,2024

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Neurology March 27,2024

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Neurology March 27,2024

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Dermatology March 27,2024

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Dermatology March 27,2024

Two new mutations identified as possible causes of rare blood disorder

by Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research SystemThis graphic shows how patients with macrothrombocytopenia and the novel GNE mutations also had excess

Pediatrics March 27,2024

Two new mutations identified as possible causes of rare blood disorder

by Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research SystemThis graphic shows how patients with macrothrombocytopenia and the novel GNE mutations also had excess

Pediatrics March 27,2024