Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Neurology April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Neurology April 09,2024

Protein activation in the brain may protect women against Alzheimer's

byKarolinska InstitutetGolgi staining of mouse brain tissue. Credit: Silvia Maioli laboratoryA new study at the Karolinska Institute suggests that activation of a certain brain protein can prote

Neurology April 09,2024

Protein activation in the brain may protect women against Alzheimer's

byKarolinska InstitutetGolgi staining of mouse brain tissue. Credit: Silvia Maioli laboratoryA new study at the Karolinska Institute suggests that activation of a certain brain protein can prote

Neurology April 09,2024

How the brain handles the complexity of chewing

by Béatrice St-Cyr-Leroux,University of MontrealConnectivity of areas involved in chewing and other orofacial behaviors. Credit:Current Opinion in Neurobiology(2023). DOI: 10.1016/j.

Neurology April 09,2024

How the brain handles the complexity of chewing

by Béatrice St-Cyr-Leroux,University of MontrealConnectivity of areas involved in chewing and other orofacial behaviors. Credit:Current Opinion in Neurobiology(2023). DOI: 10.1016/j.

Neurology April 09,2024

Key mechanisms in the synapses of the cerebellum unraveled

byInstitute of Science and Technology AustriaElectron microscope image of neurons in the cerebellum. This slice through the cells in the cerebellum shows a dendritic branch of a Purkinje cell an

Neurology April 09,2024

Key mechanisms in the synapses of the cerebellum unraveled

byInstitute of Science and Technology AustriaElectron microscope image of neurons in the cerebellum. This slice through the cells in the cerebellum shows a dendritic branch of a Purkinje cell an

Neurology April 09,2024

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Neurology April 09,2024

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Neurology April 09,2024

DNA treatment could delay paralysis that strikes nearly all patients with ALS

byUniversity of California - San DiegoAn illustration of the connections between muscle fibers and a motor neuron, the latter of which relies on crucial proteins to create and send signals to th

Neurology April 09,2024

DNA treatment could delay paralysis that strikes nearly all patients with ALS

byUniversity of California - San DiegoAn illustration of the connections between muscle fibers and a motor neuron, the latter of which relies on crucial proteins to create and send signals to th

Neurology April 09,2024

Immune genes are altered in Alzheimer's patients' blood

byNorthwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.013A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients

Neurology April 09,2024

Immune genes are altered in Alzheimer's patients' blood

byNorthwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.013A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients

Neurology April 09,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Neurology April 09,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Neurology April 09,2024

From pills to pulses: Electrifying medicine using the peripheral nervous system

byIMECBio-electronic medicine is a new form of therapy that uses electrical pulses to modulate nerve activity. The small implant delivering the pulses sits in the body, a wearable device deliver

Neurology April 09,2024

From pills to pulses: Electrifying medicine using the peripheral nervous system

byIMECBio-electronic medicine is a new form of therapy that uses electrical pulses to modulate nerve activity. The small implant delivering the pulses sits in the body, a wearable device deliver

Neurology April 09,2024

Clues to COVID-19 complications come from NET-like inflammatory response

by University of Utah Health SciencesUniversity of Utah Health critical care specialist Elizabeth Middleton, MD, treats patients with COVID-19 in the intensive care unit. A research team includin

Public Health & Prevention April 09,2024

Clues to COVID-19 complications come from NET-like inflammatory response

by University of Utah Health SciencesUniversity of Utah Health critical care specialist Elizabeth Middleton, MD, treats patients with COVID-19 in the intensive care unit. A research team includin

Public Health & Prevention April 09,2024