Type-I interferon stops immune system from 'going rogue' during viral infections

by McMaster UniversityCredit: CC0 Public DomainMcMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage.They ha

Public Health & Prevention April 16,2024

Type-I interferon stops immune system from 'going rogue' during viral infections

by McMaster UniversityCredit: CC0 Public DomainMcMaster University researchers have found not only how some viral infections cause severe tissue damage, but also how to reduce that damage.They ha

Public Health & Prevention April 16,2024

Combination of LABA + inhaled glucocorticoid safe in asthma

(HealthDay)—Compared to treatment with an inhaled glucocorticoid alone, combination therapy with a long-acting β2-agonist (LABA) and an inhaled glucocorticoid is not associated with a significantly hi

Immunology & Rheumatology April 16,2024

Combination of LABA + inhaled glucocorticoid safe in asthma

(HealthDay)—Compared to treatment with an inhaled glucocorticoid alone, combination therapy with a long-acting β2-agonist (LABA) and an inhaled glucocorticoid is not associated with a significantly hi

Immunology & Rheumatology April 16,2024

Highly active HIV antibody restricts development of viral resistance

by German Center for Infection Research(left to right): Henning Gruell, Philipp Schommers and Florian Klein. Credit: Uniklinik Koeln/Thies SchoeningAntiretroviral drugs are the gold standard for the t

Public Health & Prevention April 16,2024

Highly active HIV antibody restricts development of viral resistance

by German Center for Infection Research(left to right): Henning Gruell, Philipp Schommers and Florian Klein. Credit: Uniklinik Koeln/Thies SchoeningAntiretroviral drugs are the gold standard for the t

Public Health & Prevention April 16,2024

HIV RNA expression inhibitors may restore immune function in HIV-infected individuals

by Boston University School of MedicineHIV infecting a human cell. Credit: NIHImmune activation and inflammation persist in the majority of treated HIV-infected individuals and is associated with

Public Health & Prevention April 16,2024

HIV RNA expression inhibitors may restore immune function in HIV-infected individuals

by Boston University School of MedicineHIV infecting a human cell. Credit: NIHImmune activation and inflammation persist in the majority of treated HIV-infected individuals and is associated with

Public Health & Prevention April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Immunology & Rheumatology April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Immunology & Rheumatology April 16,2024

ISG15 deficiency linked to antiviral immunity in humans

(HealthDay)—Investigators describe a strategy for development of a broad-spectrum anti-viral agent. Their research was published online May 19 inNature Communications.Noting that studies in mice

Public Health & Prevention April 16,2024

ISG15 deficiency linked to antiviral immunity in humans

(HealthDay)—Investigators describe a strategy for development of a broad-spectrum anti-viral agent. Their research was published online May 19 inNature Communications.Noting that studies in mice

Public Health & Prevention April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Immunology & Rheumatology April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Immunology & Rheumatology April 16,2024

JAMA report outlines recommendations for evaluation and management of penicillin allergy

by Massachusetts General HospitalCredit: CC0 Public DomainWhile more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that

Breakthroughs April 16,2024

JAMA report outlines recommendations for evaluation and management of penicillin allergy

by Massachusetts General HospitalCredit: CC0 Public DomainWhile more than 32 million individuals in the U.S. have a documented penicillin allergy in their medical record, studies have shown that

Breakthroughs April 16,2024

IBD: How a class of killer T cells goes rogue in inflammatory bowel disease

by John Chang,The ConversationThe balance of memory T cell subtypes changes in individuals with ulcerative colitis. Illustrations created with BioRender.com. Credit: John ChangBetween6 and

Gastroenterology April 16,2024

IBD: How a class of killer T cells goes rogue in inflammatory bowel disease

by John Chang,The ConversationThe balance of memory T cell subtypes changes in individuals with ulcerative colitis. Illustrations created with BioRender.com. Credit: John ChangBetween6 and

Gastroenterology April 16,2024

Inflammation can lead to circadian sleep disorders

by Northwestern UniversityCredit: CC0 Public DomainInflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's dis

Immunology & Rheumatology April 16,2024

Inflammation can lead to circadian sleep disorders

by Northwestern UniversityCredit: CC0 Public DomainInflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's dis

Immunology & Rheumatology April 16,2024