ALG6 acts as a modifier gene in the inherited genetic eye disease retinitis pigmentosa 59

by Jeff Hansen,University of Alabama at BirminghamRepresentative chromatograms for each potential modifier gene. DNA from each patient sample was PCR-amplified at all five modifier sites and pur

Ophthalmology March 27,2024

ALG6 acts as a modifier gene in the inherited genetic eye disease retinitis pigmentosa 59

by Jeff Hansen,University of Alabama at BirminghamRepresentative chromatograms for each potential modifier gene. DNA from each patient sample was PCR-amplified at all five modifier sites and pur

Ophthalmology March 27,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Neurology March 27,2024

Cellular architecture of lesions in multiple sclerosis now mapped out

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainUsing advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop. The

Neurology March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Oncology March 27,2024

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

Oncology March 27,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Breakthroughs March 27,2024

The genomic architecture of inherited DNA variants

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainYou have your mother's eyes and your father's smile, but genetics is much more than just what's on th

Breakthroughs March 27,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Orthopedics & Sports medicine March 27,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Orthopedics & Sports medicine March 27,2024

Shining a light on the genetic underpinnings of a rare disease impacting children

by David McFadden,University of OttawaSynopsis. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00082-0A team from the University of Ottawa's Faculty of Medicine has completed

Pediatrics March 27,2024

Shining a light on the genetic underpinnings of a rare disease impacting children

by David McFadden,University of OttawaSynopsis. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00082-0A team from the University of Ottawa's Faculty of Medicine has completed

Pediatrics March 27,2024

Scientists discover 'powerhouse' gene, opening doors to new treatments for kidney disease

byDuke-NUS Medical SchoolDuke-NUS scientists show that the WWP2 gene plays a critical role in advancing tissue scarring in chronic kidney disease. The panels in the image demonstrate how the pre

Nephrology & Urology March 27,2024

Scientists discover 'powerhouse' gene, opening doors to new treatments for kidney disease

byDuke-NUS Medical SchoolDuke-NUS scientists show that the WWP2 gene plays a critical role in advancing tissue scarring in chronic kidney disease. The panels in the image demonstrate how the pre

Nephrology & Urology March 27,2024

Researchers support increased genomic sequencing of dengue for more effective prevention

byBoston University School of MedicineAnopheles gambiae mosquito, feeding on blood. Credit: James Gathany, Centers for Disease Control and PreventionDengue is a disease characterized by fever, r

Public Health & Prevention March 27,2024

Researchers support increased genomic sequencing of dengue for more effective prevention

byBoston University School of MedicineAnopheles gambiae mosquito, feeding on blood. Credit: James Gathany, Centers for Disease Control and PreventionDengue is a disease characterized by fever, r

Public Health & Prevention March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Neurology March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Neurology March 27,2024

Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth

byThe Spanish National Cancer Research CentreOral feeding activates a 'GPS gen' in liver cells. Credit: underbau / CNIOIn mammals, the liver detects the body's energy demand at any g

Hepatobiliary&Pancreas Surgery March 27,2024

Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth

byThe Spanish National Cancer Research CentreOral feeding activates a 'GPS gen' in liver cells. Credit: underbau / CNIOIn mammals, the liver detects the body's energy demand at any g

Hepatobiliary&Pancreas Surgery March 27,2024