Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on: January 08,2024

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on:January 08,2024

Diabetes medication class tied to lower risk of kidney stones

by Mass General BrighamCredit: Pixabay/CC0 Public DomainRates of kidney stones are on the rise in the United States and around the world. Type 2 diabetes is associated with increased risk of kidn

Updated on: May 26,2024

Diabetes medication class tied to lower risk of kidney stones

by Mass General BrighamCredit: Pixabay/CC0 Public DomainRates of kidney stones are on the rise in the United States and around the world. Type 2 diabetes is associated with increased risk of kidn

Updated on:May 26,2024

Cancer patients who don't respond to immunotherapy may lack crucial immune cells

byWashington University School of MedicineCD5+ DC frequency was reduced in tumor-affected lymph nodes, and their presence correlated with greater patient survival in multiple tumors. CD5+D

Updated on: December 20,2023

Cancer patients who don't respond to immunotherapy may lack crucial immune cells

byWashington University School of MedicineCD5+ DC frequency was reduced in tumor-affected lymph nodes, and their presence correlated with greater patient survival in multiple tumors. CD5+D

Updated on:December 20,2023

Hodgkin lymphoma survivors show signs of dementia in early adulthood

by Leslie Orr,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainIn a new study, the majority of individuals treated as children for Hodgkin lymphoma who are now in their 30s

Updated on: December 25,2023

Hodgkin lymphoma survivors show signs of dementia in early adulthood

by Leslie Orr,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainIn a new study, the majority of individuals treated as children for Hodgkin lymphoma who are now in their 30s

Updated on:December 25,2023

Novel combination of antibodies leads to significant improvement in cancer immunotherapy

byUniversity of BaselCredit: CC0 Public DomainThe simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demons

Updated on: December 20,2023

Novel combination of antibodies leads to significant improvement in cancer immunotherapy

byUniversity of BaselCredit: CC0 Public DomainThe simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demons

Updated on:December 20,2023

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on: December 30,2023

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on:December 30,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on: December 25,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on:December 25,2023

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on: January 04,2024

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on:January 04,2024

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on: December 18,2023

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on:December 18,2023

Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on: December 18,2023

Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on:December 18,2023

Anti-PF4 Immunothrombosis Absent Proximate Heparin or Adenovirus Vector Vaccine Exposure

February 2024Lara C. Pullen, PhDNew research reveals that patients with thrombocytopenia, thrombosis, and very high D-dimer levels could have platelet-activating vaccine-induced immune thrombocytopeni

Updated on: February 18,2024

Anti-PF4 Immunothrombosis Absent Proximate Heparin or Adenovirus Vector Vaccine Exposure

February 2024Lara C. Pullen, PhDNew research reveals that patients with thrombocytopenia, thrombosis, and very high D-dimer levels could have platelet-activating vaccine-induced immune thrombocytopeni

Updated on:February 18,2024