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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Surgery may add months or years of survival for adults with rare and deadly brain cancers

Surgery may add months or years of survival for adults with rare and deadly brain cancers

by Amy Mone,Johns Hopkins UniversityCredit: Alicia Ortega, MSFor adult patients with brainstem high-grade gliomas—one of the rarest and deadliest forms of brain cancer—surgically removing the en

Surgery may add months or years of survival for adults with rare and deadly brain cancers

by Amy Mone,Johns Hopkins UniversityCredit: Alicia Ortega, MSFor adult patients with brainstem high-grade gliomas—one of the rarest and deadliest forms of brain cancer—surgically removing the en
Quitting smoking tied to better survival in head, neck squamous cell carcinoma

Quitting smoking tied to better survival in head, neck squamous cell carcinoma

by Lori SolomonSmoking cessation for >10 years is significantly associated with reduced overall mortality and head and neck squamous cell carcinoma (HNSCC)-specific mortality, according to a study

Quitting smoking tied to better survival in head, neck squamous cell carcinoma

by Lori SolomonSmoking cessation for >10 years is significantly associated with reduced overall mortality and head and neck squamous cell carcinoma (HNSCC)-specific mortality, according to a study
Older US adults with certain preexisting conditions often diagnosed with poor prognosis cancers

Older US adults with certain preexisting conditions often diagnosed with poor prognosis cancers

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis published in theJournal of the American Geriatrics Societyfound that before older U.S. adults were diagnosed with poor prognosis c

Older US adults with certain preexisting conditions often diagnosed with poor prognosis cancers

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis published in theJournal of the American Geriatrics Societyfound that before older U.S. adults were diagnosed with poor prognosis c
Faulty DNA repair may lead to BRCA-linked cancers

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D
How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.
When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of
Researchers find breast cancer protein that could predict chemotherapy sensitivity

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for

Researchers find breast cancer protein that could predict chemotherapy sensitivity

by Hunter Medical Research InstituteThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for
New study may lead to fewer hysterectomies in women with uterine fibroid tumors

New study may lead to fewer hysterectomies in women with uterine fibroid tumors

by Geri Kelley, Kim Ward,Michigan State UniversityCredit: Michigan State UniversityUterine fibroid tumors are the leading cause of hysterectomies in the U.S., yet little is known about what caus

New study may lead to fewer hysterectomies in women with uterine fibroid tumors

by Geri Kelley, Kim Ward,Michigan State UniversityCredit: Michigan State UniversityUterine fibroid tumors are the leading cause of hysterectomies in the U.S., yet little is known about what caus
Protein partnership effectively fends off pancreatic cancer progression

Protein partnership effectively fends off pancreatic cancer progression

byVirginia Commonwealth UniversityModel for the functional interaction between Smad4 and Prdm16 during PDAC formation and progression. Credit:Journal of Cell Biology(2023). DOI: 10.1

Protein partnership effectively fends off pancreatic cancer progression

byVirginia Commonwealth UniversityModel for the functional interaction between Smad4 and Prdm16 during PDAC formation and progression. Credit:Journal of Cell Biology(2023). DOI: 10.1
Colorectal cancer initiation and progression: the role of low oxygen

Colorectal cancer initiation and progression: the role of low oxygen

byUniversity of LuxembourgScientists from the University of Luxembourg together with researchers from the Integrated Biobank of Luxembourg (IBBL) and the Luxembourg Institute of Health (LIH) hav

Colorectal cancer initiation and progression: the role of low oxygen

byUniversity of LuxembourgScientists from the University of Luxembourg together with researchers from the Integrated Biobank of Luxembourg (IBBL) and the Luxembourg Institute of Health (LIH) hav
Novel combination of antibodies leads to significant improvement in cancer immunotherapy

Novel combination of antibodies leads to significant improvement in cancer immunotherapy

byUniversity of BaselCredit: CC0 Public DomainThe simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demons

Novel combination of antibodies leads to significant improvement in cancer immunotherapy

byUniversity of BaselCredit: CC0 Public DomainThe simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors. This has been demons
Bringing crucial cancer treatments to rural communities

Bringing crucial cancer treatments to rural communities

by Velvet Hasner,Missouri University of Science and TechnologyCredit: Pexels image by Peter FazekasFresh air, sunsets, and a night sky full of stars are a few of the benefits to country living t

Bringing crucial cancer treatments to rural communities

by Velvet Hasner,Missouri University of Science and TechnologyCredit: Pexels image by Peter FazekasFresh air, sunsets, and a night sky full of stars are a few of the benefits to country living t