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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house
Access to Medicare increases cancer detection, reduces cancer mortality rate

Access to Medicare increases cancer detection, reduces cancer mortality rate

by Andrew Hellpap,University of Wisconsin-MadisonCredit: CC0 Public DomainAccess to Medicare significantly impacts detection of certain cancers and life expectancy following cancer diagnosis, ac

Access to Medicare increases cancer detection, reduces cancer mortality rate

by Andrew Hellpap,University of Wisconsin-MadisonCredit: CC0 Public DomainAccess to Medicare significantly impacts detection of certain cancers and life expectancy following cancer diagnosis, ac
Affordable Care Act led to improved treatment of colorectal cancer among young adults

Affordable Care Act led to improved treatment of colorectal cancer among young adults

byAmerican Cancer SocietyCredit: CC0 Public DomainAn Affordable Care Act provision that allowed young adults to be covered under their parents' insurance led to a shift to earlier-stage diag

Affordable Care Act led to improved treatment of colorectal cancer among young adults

byAmerican Cancer SocietyCredit: CC0 Public DomainAn Affordable Care Act provision that allowed young adults to be covered under their parents' insurance led to a shift to earlier-stage diag
Researchers clarify role of SMYD3 enzyme in prostate cancer progression

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal

Researchers clarify role of SMYD3 enzyme in prostate cancer progression

by Sarah Hansen,University of Maryland Baltimore CountySMYD3 loss impedes PCa progression.(A) Expression ofSMYD3mRNA from TCGA [GTEX normal (n= 105), TCGA tumor adjacent normal
Detailed diagnosis boosts child cancer survival

Detailed diagnosis boosts child cancer survival

byCancer Research UK| News6 March 2009More accurate disease classification now means some young children with neuroblastoma will have less intensive treatment with better survival, accordi

Detailed diagnosis boosts child cancer survival

byCancer Research UK| News6 March 2009More accurate disease classification now means some young children with neuroblastoma will have less intensive treatment with better survival, accordi
When cells cycle fast, cancer gets a jumpstart

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions

When cells cycle fast, cancer gets a jumpstart

byYale UniversityCredit: CC0 Public DomainThe progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions
Shutting down backup genes leads to cancer remission in mice

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer
Why lung cancer doesn't respond well to immunotherapy

Why lung cancer doesn't respond well to immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyA new MIT study explains why dendritic cells (green) in lymph nodes that drain from the lungs fail to stimulate killer T cells (white) to att

Why lung cancer doesn't respond well to immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyA new MIT study explains why dendritic cells (green) in lymph nodes that drain from the lungs fail to stimulate killer T cells (white) to att
RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population

RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses ac

RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses ac
Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B
Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung
Refined method to peer into cancer cells' inner working unlocks the interactome

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR