Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on: January 30,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on:January 30,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on: February 01,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on:February 01,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on: March 30,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on:March 30,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on: March 01,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on:March 01,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on: June 28,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on:June 28,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on: June 24,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on:June 24,2024

Researchers pursue blood test for colorectal cancer

by West Virginia UniversityBonnie's Bus is a mobile mammography unit that the WVU Cancer Institute uses to conduct breast cancer screenings across West Virginia, even in rural counties that a

Updated on: June 04,2024

Researchers pursue blood test for colorectal cancer

by West Virginia UniversityBonnie's Bus is a mobile mammography unit that the WVU Cancer Institute uses to conduct breast cancer screenings across West Virginia, even in rural counties that a

Updated on:June 04,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on: June 08,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on:June 08,2024