Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on: February 23,2024

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on:February 23,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on: April 22,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on:April 22,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on: January 12,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on:January 12,2024

Stress granules may drive obesity-associated pancreatic cancer

byThomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainObesity is a known risk factor for at least13 types of cancer, in part because it creates ever-present inflammatory state. For

Updated on: January 16,2024

Stress granules may drive obesity-associated pancreatic cancer

byThomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainObesity is a known risk factor for at least13 types of cancer, in part because it creates ever-present inflammatory state. For

Updated on:January 16,2024

Study finds worsening metabolic syndrome increases the risk of developing cancer

by WileyCredit: Pavel Danilyuk from PexelsNew research indicates that individuals with persistent and worsening metabolic syndrome—which encompasses conditions such as high blood pressure, elevat

Updated on: March 20,2024

Study finds worsening metabolic syndrome increases the risk of developing cancer

by WileyCredit: Pavel Danilyuk from PexelsNew research indicates that individuals with persistent and worsening metabolic syndrome—which encompasses conditions such as high blood pressure, elevat

Updated on:March 20,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Researchers identify a test to target cancer drug

by University of LeedsKiller T cells surround a cancer cell. Credit: NIHDoctors are developing a more personalised approach to the treatment of bowel cancer, thanks to research which has found a

Updated on: June 06,2024

Researchers identify a test to target cancer drug

by University of LeedsKiller T cells surround a cancer cell. Credit: NIHDoctors are developing a more personalised approach to the treatment of bowel cancer, thanks to research which has found a

Updated on:June 06,2024

Pregnancy poses no greater risk to breast cancer survivors

by Oxford University PressCredit: CC0 Public DomainA recent study published in theJournal of the National Cancer Instituteindicates that pregnancy does not incur a greater risk of rel

Updated on: March 06,2024

Pregnancy poses no greater risk to breast cancer survivors

by Oxford University PressCredit: CC0 Public DomainA recent study published in theJournal of the National Cancer Instituteindicates that pregnancy does not incur a greater risk of rel

Updated on:March 06,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on: February 18,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on:February 18,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on: June 04,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on:June 04,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on: January 23,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on:January 23,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on: February 20,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on:February 20,2024