A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on: January 29,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on:January 29,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on: March 06,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on:March 06,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on: June 28,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on:June 28,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on: March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on:March 06,2024

Study reveals proton beam therapy may shorten breast cancer treatment

by Mayo ClinicCredit: Mayo ClinicIn a randomized trial, published inThe Lancet Oncology,Mayo Clinic Comprehensive Cancer Center researchers uncover evidence supporting a shorter treat

Updated on: January 30,2024

Study reveals proton beam therapy may shorten breast cancer treatment

by Mayo ClinicCredit: Mayo ClinicIn a randomized trial, published inThe Lancet Oncology,Mayo Clinic Comprehensive Cancer Center researchers uncover evidence supporting a shorter treat

Updated on:January 30,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on: May 25,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on:May 25,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on: April 20,2024

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on:April 20,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

'You have lung cancer' UK patients told in Xmas error

Credit: Pixabay/CC0 Public DomainA doctors' surgery in England has apologised after sending patients a text telling them they had advanced lung cancer instead of wishing them a merry Christmas, re

Updated on: February 18,2024

'You have lung cancer' UK patients told in Xmas error

Credit: Pixabay/CC0 Public DomainA doctors' surgery in England has apologised after sending patients a text telling them they had advanced lung cancer instead of wishing them a merry Christmas, re

Updated on:February 18,2024