Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on: February 20,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on:February 20,2024

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on: January 22,2024

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on:January 22,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on: March 05,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on:March 05,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on: February 18,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on:February 18,2024

Active surveillance feasible for small, low-grade bladder cancer

(HealthDay)—For patients who present with small, low-grade pTa/pT1a recurrent papillary bladder tumors, active surveillance appears to be a reasonable strategy, according to a study published in the F

Updated on: April 07,2024

Active surveillance feasible for small, low-grade bladder cancer

(HealthDay)—For patients who present with small, low-grade pTa/pT1a recurrent papillary bladder tumors, active surveillance appears to be a reasonable strategy, according to a study published in the F

Updated on:April 07,2024

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on: February 18,2024

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on:February 18,2024

A new therapeutic strategy to improve treatment of aggressive endometrial cancer

by Autonomous University of BarcelonaERK5 inhibition impairs EC cell proliferation.AGenomic profiles of components of the MEK5-ERK5 pathway in EC patients obtained from Uterine Corpus

Updated on: February 23,2024

A new therapeutic strategy to improve treatment of aggressive endometrial cancer

by Autonomous University of BarcelonaERK5 inhibition impairs EC cell proliferation.AGenomic profiles of components of the MEK5-ERK5 pathway in EC patients obtained from Uterine Corpus

Updated on:February 23,2024

Research examines how to stay on task

by University of Texas at ArlingtonTask paradigm visual for a single trial on the four-choice reaction time task. Credit:Attention, Perception, & Psychophysics(2023). DOI: 10.3758

Updated on: March 12,2024

Research examines how to stay on task

by University of Texas at ArlingtonTask paradigm visual for a single trial on the four-choice reaction time task. Credit:Attention, Perception, & Psychophysics(2023). DOI: 10.3758

Updated on:March 12,2024

Trends in genitourinary cancers examined in the United States

by Elana GotkineThe highest incidence rates of bladder cancer are seen in the Northeast, while the West has the highest deaths rates for prostate cancer among non-Hispanic White men, according to a st

Updated on: January 02,2024

Trends in genitourinary cancers examined in the United States

by Elana GotkineThe highest incidence rates of bladder cancer are seen in the Northeast, while the West has the highest deaths rates for prostate cancer among non-Hispanic White men, according to a st

Updated on:January 02,2024

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,

Updated on: March 01,2024

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,

Updated on:March 01,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024