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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (
Precision oncology insights revealed for colorectal cancer

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to
First major study of proteins in patients with acute lymphoblastic leukaemia

First major study of proteins in patients with acute lymphoblastic leukaemia

by Lund UniversityA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaThe most common form of childhood ca

First major study of proteins in patients with acute lymphoblastic leukaemia

by Lund UniversityA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaThe most common form of childhood ca
Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
'Fighting' cancer may detract men from palliative care

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re
Novel bioassay predicts cancer patients' response to immunotherapy

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ
Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t
Improving CAR T-cell and monoclonal antibody treatment through epitope editing

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t
Study shines light on cancer survival and a key gene mutation

Study shines light on cancer survival and a key gene mutation

by University of TorontoScientists and doctors have known about the p53 gene for a long time, and that it plays a role in halting tumour growth. Credit: Hush Naidoo via UnsplashUniversity of Toro

Study shines light on cancer survival and a key gene mutation

by University of TorontoScientists and doctors have known about the p53 gene for a long time, and that it plays a role in halting tumour growth. Credit: Hush Naidoo via UnsplashUniversity of Toro
Adhering to global health recommendations reduces cancer risk

Adhering to global health recommendations reduces cancer risk

byNewcastle UniversityCredit: CC0 Public DomainPeople who adhere to global Cancer Prevention Recommendations are putting themselves at lower risk of developing the disease, new research confirms

Adhering to global health recommendations reduces cancer risk

byNewcastle UniversityCredit: CC0 Public DomainPeople who adhere to global Cancer Prevention Recommendations are putting themselves at lower risk of developing the disease, new research confirms
Next milestone in the treatment of liver tumors and acute and chronic liver diseases

Next milestone in the treatment of liver tumors and acute and chronic liver diseases

by Bianca Hermle, Universitätsklinikum TübingenGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.02.023The results of a Tübingen-led study raise hope that a newly developed d

Next milestone in the treatment of liver tumors and acute and chronic liver diseases

by Bianca Hermle, Universitätsklinikum TübingenGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.02.023The results of a Tübingen-led study raise hope that a newly developed d