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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong
Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study

by Impact Journals LLCLung adenocarcinoma histochemistry. Representative sections illustrating tumor HA histochemistry staining (Ventana HA RxDx Assay) in FFPE lung adenocarcinoma samples scored as HA

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study

by Impact Journals LLCLung adenocarcinoma histochemistry. Representative sections illustrating tumor HA histochemistry staining (Ventana HA RxDx Assay) in FFPE lung adenocarcinoma samples scored as HA
Researchers edge closer to delivering personalized medicine to cancer patients

Researchers edge closer to delivering personalized medicine to cancer patients

FEBRUARY 14, 2024byPurdue UniversityDr. Michael Childress (right), Professor of Comparative Oncology at the Purdue University College of Veterinary Medicine, is pictured with Kody (middle) and h

Researchers edge closer to delivering personalized medicine to cancer patients

FEBRUARY 14, 2024byPurdue UniversityDr. Michael Childress (right), Professor of Comparative Oncology at the Purdue University College of Veterinary Medicine, is pictured with Kody (middle) and h
Software program that looks for the most effective drugs helps to personalize cancer treatments

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char
Researchers discover the Achilles' heel of an aggressive brain cancer

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen
Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet
Novel theranostic tool allows for noninvasive identification and treatment of ovarian cancer

Novel theranostic tool allows for noninvasive identification and treatment of ovarian cancer

by Society of Nuclear MedicineA radiotheranostic platform that employs a MUC16-targeting humanized antibody, huAR9.6. Ovarian cancer cells that express hypoglycosylated MUC16 residues are detecte

Novel theranostic tool allows for noninvasive identification and treatment of ovarian cancer

by Society of Nuclear MedicineA radiotheranostic platform that employs a MUC16-targeting humanized antibody, huAR9.6. Ovarian cancer cells that express hypoglycosylated MUC16 residues are detecte
Direct-to-consumer cancer testing could be beneficial, expert says, but it's not a substitute

Direct-to-consumer cancer testing could be beneficial, expert says, but it's not a substitute

by Leha Byrd,Virginia Commonwealth UniversityWhile the availability of direct-to-consumer genetic testing could be helpful, it also should not dissuade people from seeking professional advice re

Direct-to-consumer cancer testing could be beneficial, expert says, but it's not a substitute

by Leha Byrd,Virginia Commonwealth UniversityWhile the availability of direct-to-consumer genetic testing could be helpful, it also should not dissuade people from seeking professional advice re
Discovery could lead to new drugs to block protein that fuels bowel cancer

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc
Novel approach to study hypoxia enables identification of a marker for ovarian cancers

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795
Increased mitochondria and lipid turnover reduces risk for liver cancer

Increased mitochondria and lipid turnover reduces risk for liver cancer

by University of Chicago Medical CenterLoss of BNIP3 promotes HCC initiation and tumor growth. (A) Representative images of HCC tumors forming in the liver of Bnip3+/+and bnip3−/−mice

Increased mitochondria and lipid turnover reduces risk for liver cancer

by University of Chicago Medical CenterLoss of BNIP3 promotes HCC initiation and tumor growth. (A) Representative images of HCC tumors forming in the liver of Bnip3+/+and bnip3−/−mice
Merck, Moderna detail potential skin cancer vaccine progress

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p