Allogeneic HCT after primary induction failure beneficial in leukemia

by Elana GotkineFor patients with acute myeloid leukemia (AML), immediate allogeneic hematopoietic stem cell transplantation (HCT) after primary induction failure (PIF) offers long-term survival benef

Updated on: December 26,2023 16

Allogeneic HCT after primary induction failure beneficial in leukemia

by Elana GotkineFor patients with acute myeloid leukemia (AML), immediate allogeneic hematopoietic stem cell transplantation (HCT) after primary induction failure (PIF) offers long-term survival benef

Updated on:December 26,2023 16

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on: December 21,2023 8

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on:December 21,2023 8

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on: December 18,2023 17

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on:December 18,2023 17

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on: October 30,2023 29

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on:October 30,2023 29

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023 7

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023 7

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on: October 30,2023 22

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on:October 30,2023 22

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on: December 27,2023 10

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on:December 27,2023 10

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on: December 19,2023 10

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on:December 19,2023 10

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on: December 19,2023 10

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on:December 19,2023 10

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on: December 20,2023 10

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on:December 20,2023 10

AI tool reveals cardiac risk for patients undergoing cancer therapy

byYale School of MedicineBaseline AI-ECG screening for LVSD and all-cause mortality risk. Adjusted cumulative hazard curves for all-cause mortality stratified by the AI-ECG LVSD probability. Cre

Updated on: September 27,2024 0

AI tool reveals cardiac risk for patients undergoing cancer therapy

byYale School of MedicineBaseline AI-ECG screening for LVSD and all-cause mortality risk. Adjusted cumulative hazard curves for all-cause mortality stratified by the AI-ECG LVSD probability. Cre

Updated on:September 27,2024 0

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demons

Updated on: October 28,2023 16

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demons

Updated on:October 28,2023 16