Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi

Updated on: November 10,2024

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi

Updated on:November 10,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on: November 10,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on:November 10,2024

Researchers identify feature of early stage colorectal cancer tumors that signals aggressiveness

by Cheryl Critchley,Monash UniversityOncogenic KRAS-driven MAPK signaling confers tolerance to epithelial TGFβ activation. a Representative H&E and Alk5 ISH of small intestinal tissue from V

Updated on: February 20,2024

Researchers identify feature of early stage colorectal cancer tumors that signals aggressiveness

by Cheryl Critchley,Monash UniversityOncogenic KRAS-driven MAPK signaling confers tolerance to epithelial TGFβ activation. a Representative H&E and Alk5 ISH of small intestinal tissue from V

Updated on:February 20,2024

Cancer patients can quit smoking through lengthened medication time, counseling support

by Northwestern UniversityCredit: CC0 Public DomainQuitting smoking can significantly improve the effectiveness of cancer treatment, according to theU.S. Surgeon General,yet almost ha

Updated on: March 09,2024

Cancer patients can quit smoking through lengthened medication time, counseling support

by Northwestern UniversityCredit: CC0 Public DomainQuitting smoking can significantly improve the effectiveness of cancer treatment, according to theU.S. Surgeon General,yet almost ha

Updated on:March 09,2024

Exercise could reduce frailty in the most common form of leukemia

by University of SurreyCredit: Pixabay/CC0 Public DomainIncreased levels of exercise could help reduce frailty in patients with the most common form of leukemia, chronic lymphocytic (CLL), accord

Updated on: January 29,2024

Exercise could reduce frailty in the most common form of leukemia

by University of SurreyCredit: Pixabay/CC0 Public DomainIncreased levels of exercise could help reduce frailty in patients with the most common form of leukemia, chronic lymphocytic (CLL), accord

Updated on:January 29,2024

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on: January 22,2024

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on:January 22,2024

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on: January 04,2024

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on:January 04,2024

Study finds Medicaid expansion improves cancer survival outcomes for young adults

byEmory UniversityCredit: Unsplash/CC0 Public DomainA large first-of-its-kind study reported in theJournal of Clinical Oncologyfinds that expanded Medicaid coverage under the Afforda

Updated on: January 23,2024

Study finds Medicaid expansion improves cancer survival outcomes for young adults

byEmory UniversityCredit: Unsplash/CC0 Public DomainA large first-of-its-kind study reported in theJournal of Clinical Oncologyfinds that expanded Medicaid coverage under the Afforda

Updated on:January 23,2024

A window into the changing tumor microenvironment

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104570Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce

Updated on: February 18,2024

A window into the changing tumor microenvironment

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104570Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce

Updated on:February 18,2024

Allogenic hematopoietic cell transplant a viable option for high-risk myelodysplastic syndrome, study suggests

byDana-Farber Cancer InstituteClinical outcomes by TP53 allelic state. (A) OS by TP53 allelic state. (B) Cumulative incidence of MDS relapse or progression to AML by TP53 allelic state, with dea

Updated on: January 16,2024

Allogenic hematopoietic cell transplant a viable option for high-risk myelodysplastic syndrome, study suggests

byDana-Farber Cancer InstituteClinical outcomes by TP53 allelic state. (A) OS by TP53 allelic state. (B) Cumulative incidence of MDS relapse or progression to AML by TP53 allelic state, with dea

Updated on:January 16,2024

Treatment with immunotherapy alone produces 'exceptional' response rates in some melanoma patients

by Ohio State University Medical CenterMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Data from a national clinic

Updated on: February 03,2024

Treatment with immunotherapy alone produces 'exceptional' response rates in some melanoma patients

by Ohio State University Medical CenterMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Data from a national clinic

Updated on:February 03,2024

Biosensors for bladder cancer diagnosis

by University of BathCredit: AI-generated imageCancer constitutes one of the leading causes of mortality worldwide. As early diagnosis is paramount to improved clinical outcome and survival, sens

Updated on: May 09,2024

Biosensors for bladder cancer diagnosis

by University of BathCredit: AI-generated imageCancer constitutes one of the leading causes of mortality worldwide. As early diagnosis is paramount to improved clinical outcome and survival, sens

Updated on:May 09,2024