Exploring key regulators of programmed cell death in melanoma and the immune system's response

byBrigham and Women’s HospitalExpression of type I interferon receptors by melanoma cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51496-2A new paperpublish

Updated on: September 10,2024

Exploring key regulators of programmed cell death in melanoma and the immune system's response

byBrigham and Women’s HospitalExpression of type I interferon receptors by melanoma cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51496-2A new paperpublish

Updated on:September 10,2024

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on: December 20,2023

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on:December 20,2023

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on: December 20,2023

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on:December 20,2023

Daratumumab Plus Induction Therapy Reduces Stem Cell Yield in Multiple Myeloma

June 9, 2023Tony Berberabe, MPHThe addition of daratumumab to frontline induction therapy prior to peripheral blood stem cell collection reduced the number of patients with newly diagnosed multiple my

Updated on: October 12,2023

Daratumumab Plus Induction Therapy Reduces Stem Cell Yield in Multiple Myeloma

June 9, 2023Tony Berberabe, MPHThe addition of daratumumab to frontline induction therapy prior to peripheral blood stem cell collection reduced the number of patients with newly diagnosed multiple my

Updated on:October 12,2023

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on: October 30,2023

Are inflammatory bowel disease patients more at risk of colorectal cancer

In a recent study published in the journalFrontiers in Medicine, researchers analyzed data from a large cohort of inflammatory bowel disease (IBD) patients and compared the risk and frequency of

Updated on:October 30,2023

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on: December 21,2023

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on:December 21,2023

Unraveling of genetic mechanism behind tumor formation may improve targeted treatment for cancer patients

by Rutgers Cancer Institute of New JerseyCredit: Pixabay/CC0 Public DomainGenetic alterations in the FGFR2 gene occur in various cancer types and represent a promising target for therapies. However, c

Updated on: December 18,2023

Unraveling of genetic mechanism behind tumor formation may improve targeted treatment for cancer patients

by Rutgers Cancer Institute of New JerseyCredit: Pixabay/CC0 Public DomainGenetic alterations in the FGFR2 gene occur in various cancer types and represent a promising target for therapies. However, c

Updated on:December 18,2023

Leukemia vulnerability discovered causing drug sensitivity

byJosep Carreras Leukaemia Research InstituteCells from acute lymphoblastic leukemia, a disease against which treatment with glutathione inhibitors has demonstrated preclinical efficacy, dying b

Updated on: December 22,2023

Leukemia vulnerability discovered causing drug sensitivity

byJosep Carreras Leukaemia Research InstituteCells from acute lymphoblastic leukemia, a disease against which treatment with glutathione inhibitors has demonstrated preclinical efficacy, dying b

Updated on:December 22,2023

Research collaboration reveals promising drug candidate for treatment of blood cancers

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainToday, OncoTartis, Inc. and Children's Cancer Institute jointly announced the publication of two research manuscripts in a lead

Updated on: December 20,2023

Research collaboration reveals promising drug candidate for treatment of blood cancers

by Children's Cancer Institute AustraliaCredit: CC0 Public DomainToday, OncoTartis, Inc. and Children's Cancer Institute jointly announced the publication of two research manuscripts in a lead

Updated on:December 20,2023

Cell therapy could improve bone marrow transplant safety

by Tiare Dunlap,University of California, Los AngelesGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104859UCLA researchers report a step forward in the developme

Updated on: January 10,2024

Cell therapy could improve bone marrow transplant safety

by Tiare Dunlap,University of California, Los AngelesGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104859UCLA researchers report a step forward in the developme

Updated on:January 10,2024

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on: December 22,2023

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on:December 22,2023

Sub-lobar surgery for peripheral non-small cell lung cancer non-inferior to lobectomy

by International Association for the Study of Lung CancerCancer cell during cell division. Credit: National Institutes of HealthA large international study of patients with non-small cell lung cancer

Updated on: December 18,2023

Sub-lobar surgery for peripheral non-small cell lung cancer non-inferior to lobectomy

by International Association for the Study of Lung CancerCancer cell during cell division. Credit: National Institutes of HealthA large international study of patients with non-small cell lung cancer

Updated on:December 18,2023