CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on: February 18,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on:February 18,2024

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on: March 25,2024

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on:March 25,2024

Cancer diagnosis can be devastating, but for some it gives permission to live more radically

by Kevin Dew, Alex Broom, Chris Cunningham, Elizabeth Dennett, Kerry Chamberlain and Richard Egan,The ConversationCredit: Ivan Samkov from PexelsA diagnosis of life-limiting cancer can be overwh

Updated on: August 28,2024

Cancer diagnosis can be devastating, but for some it gives permission to live more radically

by Kevin Dew, Alex Broom, Chris Cunningham, Elizabeth Dennett, Kerry Chamberlain and Richard Egan,The ConversationCredit: Ivan Samkov from PexelsA diagnosis of life-limiting cancer can be overwh

Updated on:August 28,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells

Updated on: May 27,2024

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells

Updated on:May 27,2024

Hunting brain cancer cells: Neuronal and tumorigenic boundaries of glioblastoma plasticity

byFlinders UniversityGlioblastoma tumor cells express aberrant neuronal signatures and differentiate along a neurodevelopmental trajectory. (A) Healthy neuronal cells transform to a malignant ph

Updated on: January 15,2024

Hunting brain cancer cells: Neuronal and tumorigenic boundaries of glioblastoma plasticity

byFlinders UniversityGlioblastoma tumor cells express aberrant neuronal signatures and differentiate along a neurodevelopmental trajectory. (A) Healthy neuronal cells transform to a malignant ph

Updated on:January 15,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

Researchers investigate cancer cluster in Alabama town

by Lindsey Piercy,University of KentuckyCredit: Unsplash/CC0 Public DomainFruithurst is your quintessential small town. Located in Cleburne County, Alabama—just five miles on the other side of t

Updated on: February 20,2024

Researchers investigate cancer cluster in Alabama town

by Lindsey Piercy,University of KentuckyCredit: Unsplash/CC0 Public DomainFruithurst is your quintessential small town. Located in Cleburne County, Alabama—just five miles on the other side of t

Updated on:February 20,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on: March 06,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on:March 06,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on: March 30,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on:March 30,2024