Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on: December 25,2023

Antibody-based therapy eliminates circulating tumor cells in mouse models of breast and pancreatic cancer

by Katie Marquedant,Massachusetts General Hospital(A) Schema for the mouse models of neoadjuvant placebo or 23C6 treatment. (B) Tumor volume measurements of 4T1 orthotopic mammary gland tumors i

Updated on:December 25,2023

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on: December 25,2023

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on:December 25,2023

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024

Review paper compares two leading pancreatic cancer drugs

by Tyrel Linkhorn,University of ToledoPotential biomarkers in nab-paclitaxel/gemcitabine (a), Folfirinox (b) regimens of drug metabolism and mechanism of action. (c) Macrophages induce gemcitabi

Updated on: May 07,2024

Review paper compares two leading pancreatic cancer drugs

by Tyrel Linkhorn,University of ToledoPotential biomarkers in nab-paclitaxel/gemcitabine (a), Folfirinox (b) regimens of drug metabolism and mechanism of action. (c) Macrophages induce gemcitabi

Updated on:May 07,2024

Researchers urge caution in co-prescribing potency drugs and nitrates

by Karolinska InstitutetCredit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.041Co-prescribing potency drugs such as Viagra and organic nitrates for

Updated on: May 06,2024

Researchers urge caution in co-prescribing potency drugs and nitrates

by Karolinska InstitutetCredit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.041Co-prescribing potency drugs such as Viagra and organic nitrates for

Updated on:May 06,2024

Could that breast pain be cancer? When to get a mammogram

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainIf you've ever felt pain, tenderness and tightness—maybe even a sharp, stabbing sensation—in your breasts, it's hard not

Updated on: January 02,2024

Could that breast pain be cancer? When to get a mammogram

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainIf you've ever felt pain, tenderness and tightness—maybe even a sharp, stabbing sensation—in your breasts, it's hard not

Updated on:January 02,2024

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on: December 30,2023

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on:December 30,2023

New pancreatic cancer treatment proves effective in shrinking, clearing tumors

byUniversity of Massachusetts AmherstPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteResearchers at the University of Massachusett

Updated on: September 07,2024

New pancreatic cancer treatment proves effective in shrinking, clearing tumors

byUniversity of Massachusetts AmherstPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteResearchers at the University of Massachusett

Updated on:September 07,2024

A breast cancer drug, susceptible to resistance, can be restored to effectiveness, researchers demonstrate

by Leslie Cantu,Medical University of South CarolinaCredit: Pixabay/CC0 Public DomainIn a new paperpublishedinCancer Research, researchers at MUSC Hollings Cancer Center have s

Updated on: May 06,2024

A breast cancer drug, susceptible to resistance, can be restored to effectiveness, researchers demonstrate

by Leslie Cantu,Medical University of South CarolinaCredit: Pixabay/CC0 Public DomainIn a new paperpublishedinCancer Research, researchers at MUSC Hollings Cancer Center have s

Updated on:May 06,2024

Engineered peptides open new avenue for immunotherapy drug development

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainIn a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cance

Updated on: May 14,2024

Engineered peptides open new avenue for immunotherapy drug development

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainIn a new study published in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cance

Updated on:May 14,2024

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on: December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on:December 25,2023

Immunotherapy shows potential to treat deadly thyroid cancer

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results o

Updated on: November 30,2024

Immunotherapy shows potential to treat deadly thyroid cancer

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results o

Updated on:November 30,2024