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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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First immunotherapy success for triple-negative breast cancer

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by
Q and A: Is surgery best for an acoustic neuroma?

Q and A: Is surgery best for an acoustic neuroma?

by Joseph BreenCredit: Pixabay/CC0 Public DomainI was diagnosed with an acoustic neuroma last year after I went to the doctor due to more frequent headaches. I read that surgery often is needed for th

Q and A: Is surgery best for an acoustic neuroma?

by Joseph BreenCredit: Pixabay/CC0 Public DomainI was diagnosed with an acoustic neuroma last year after I went to the doctor due to more frequent headaches. I read that surgery often is needed for th
UC San Diego Moores administers its first personalized cancer vaccine

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round
Seeking leukemia's Achilles heel

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h
Researchers identify molecular characteristics of leptomeningeal melanoma metastases

Researchers identify molecular characteristics of leptomeningeal melanoma metastases

byH. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Patients w

Researchers identify molecular characteristics of leptomeningeal melanoma metastases

byH. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Patients w
Novel therapeutic targets discovered for triple-negative breast cancer

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of
Can the flu shot help fight cancer?

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and
New cell-based immunotherapy offered for melanoma

New cell-based immunotherapy offered for melanoma

by Julia Evangelou Strait,Washington University School of Medicine in St. LouisCredit: Pixabay/CC0 Public DomainSiteman Cancer Center, based at Barnes-Jewish Hospital and Washington University S

New cell-based immunotherapy offered for melanoma

by Julia Evangelou Strait,Washington University School of Medicine in St. LouisCredit: Pixabay/CC0 Public DomainSiteman Cancer Center, based at Barnes-Jewish Hospital and Washington University S
CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung
Iflinatamab Deruxtecan Elicits Clinical Activity in SCLC

Iflinatamab Deruxtecan Elicits Clinical Activity in SCLC

September 10, 2023Jonah FeldmanTreatment with the antibody-drug conjugate ifinatamab deruxtecan in heavily pretreated patients with small cell lung cancer led to promising efficacy and a manageable sa

Iflinatamab Deruxtecan Elicits Clinical Activity in SCLC

September 10, 2023Jonah FeldmanTreatment with the antibody-drug conjugate ifinatamab deruxtecan in heavily pretreated patients with small cell lung cancer led to promising efficacy and a manageable sa
FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a
Tracking genes to fight breast cancer

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es