Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on: August 01,2024

Drug-like molecules show early success in targeting breast cancer brain metastases

byDrexel UniversityComputational pipeline and predicted drug-like properties for the discovery of AD-2441 and its analogs. Credit:Frontiers in Pharmacology(2024). DOI: 10.3389/fphar.

Updated on:August 01,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on: May 20,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on:May 20,2024

How metastatic cancer causes leaky blood vessels

byAmerican Institute of PhysicsImmunofluorescence images showing the effects of contactless paracrine signaling interactions (left) or physical contact (right) in micropatterned endothelial cell

Updated on: January 22,2024

How metastatic cancer causes leaky blood vessels

byAmerican Institute of PhysicsImmunofluorescence images showing the effects of contactless paracrine signaling interactions (left) or physical contact (right) in micropatterned endothelial cell

Updated on:January 22,2024

Researchers extend effectiveness of immunotherapy to more lung cancer patients

by The Spanish National Cancer Research CentreCredit: CC0 Public DomainImmunotherapy, the strategy for triggering the patient's own immune system to attack cancer, is proving effective for mo

Updated on: March 12,2024

Researchers extend effectiveness of immunotherapy to more lung cancer patients

by The Spanish National Cancer Research CentreCredit: CC0 Public DomainImmunotherapy, the strategy for triggering the patient's own immune system to attack cancer, is proving effective for mo

Updated on:March 12,2024

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c

Updated on: March 12,2024

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c

Updated on:March 12,2024

Rare but important gene target found in many tumor types, suggesting new therapy possible

by Georgetown University Medical CenterStephen V. Liu, MD, an associate professor of medicine at Georgetown Lombardi Comprehensive Cancer Center. Credit: Georgetown UniversityA consortium of rese

Updated on: April 20,2024

Rare but important gene target found in many tumor types, suggesting new therapy possible

by Georgetown University Medical CenterStephen V. Liu, MD, an associate professor of medicine at Georgetown Lombardi Comprehensive Cancer Center. Credit: Georgetown UniversityA consortium of rese

Updated on:April 20,2024

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r

Updated on: February 18,2024

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r

Updated on:February 18,2024

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12

Updated on: January 23,2024

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12

Updated on:January 23,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on: May 07,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on:May 07,2024

Researchers edge closer to delivering personalized medicine to cancer patients

FEBRUARY 14, 2024byPurdue UniversityDr. Michael Childress (right), Professor of Comparative Oncology at the Purdue University College of Veterinary Medicine, is pictured with Kody (middle) and h

Updated on: March 28,2024

Researchers edge closer to delivering personalized medicine to cancer patients

FEBRUARY 14, 2024byPurdue UniversityDr. Michael Childress (right), Professor of Comparative Oncology at the Purdue University College of Veterinary Medicine, is pictured with Kody (middle) and h

Updated on:March 28,2024

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on: June 15,2024

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on:June 15,2024

Decrease in breast cancer mortality rate continues. Wide gap for Black women remains stagnant

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainWhile breast cancer death rates dropped by 43% from 1989 to 2020, Black women continue to be 40% more likely to die from the disease de

Updated on: January 03,2024

Decrease in breast cancer mortality rate continues. Wide gap for Black women remains stagnant

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainWhile breast cancer death rates dropped by 43% from 1989 to 2020, Black women continue to be 40% more likely to die from the disease de

Updated on:January 03,2024