Study unravels a cause of resistance to novel drug in patients with acute leukemia

by Dana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainA new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells t

Updated on: February 23,2024

Study unravels a cause of resistance to novel drug in patients with acute leukemia

by Dana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainA new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells t

Updated on:February 23,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on: June 04,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on:June 04,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on: June 08,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on:June 08,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on: June 24,2024

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on:June 24,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024

Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on: April 06,2024

Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on:April 06,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on: April 10,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on:April 10,2024

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on: April 18,2024

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on:April 18,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024