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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Mechanism identified for drug resistance in glioblastoma brain tumors

Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha

Mechanism identified for drug resistance in glioblastoma brain tumors

by Sarah Avery,Duke UniversityPro-tumor immune programming in the glioma microenvironment is CaMKK2 dependent. a Schematic depicting scRNA-seq experimental design. n = 4 WT and CaMKK2 KO mice ha
New tool helps find genetic culprits in cancer's spread

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale
Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant

Advanced melanoma survival improves significantly when immunotherapy is given before targeted therapy

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advant
Study demonstrates antitumor action of substance present in Brazilian green propolis

Study demonstrates antitumor action of substance present in Brazilian green propolis

FEBRUARY 7, 2024byFAPESPLDH assay representing the percentage of membrane integrity damage obtained for fibroblast (A) and glioblastoma (B) cell lines, after 24 h incubation, exposed to 0, 1, 10

Study demonstrates antitumor action of substance present in Brazilian green propolis

FEBRUARY 7, 2024byFAPESPLDH assay representing the percentage of membrane integrity damage obtained for fibroblast (A) and glioblastoma (B) cell lines, after 24 h incubation, exposed to 0, 1, 10
A new antibody capture method reveals G-quadruplex landscape and its regulation

A new antibody capture method reveals G-quadruplex landscape and its regulation

by Impact Journals LLCA comparative analysis of G4 landscape in cultured cells usingAbCG4-ChIP. (A) A schematic of the conventional G4-ChIP highlighting the possibilities of false positive

A new antibody capture method reveals G-quadruplex landscape and its regulation

by Impact Journals LLCA comparative analysis of G4 landscape in cultured cells usingAbCG4-ChIP. (A) A schematic of the conventional G4-ChIP highlighting the possibilities of false positive
Survivorship portal brings cancer researchers one click away from discovery

Survivorship portal brings cancer researchers one click away from discovery

bySt. Jude Children's Research HospitalCredit: Pixabay/CC0 Public DomainScientists from St. Jude Children's Research Hospital today announced the St. Judesurvivorship portal—the fi

Survivorship portal brings cancer researchers one click away from discovery

bySt. Jude Children's Research HospitalCredit: Pixabay/CC0 Public DomainScientists from St. Jude Children's Research Hospital today announced the St. Judesurvivorship portal—the fi
Researchers determine oral bacteria accelerate pancreatic cancer development in mice

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of
Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga
New treatment trialed in mice offers hope for advanced liver cancer

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat
Continued access to fertility preservation is critical for teens and young adult cancer patients after SCOTUS decision

Continued access to fertility preservation is critical for teens and young adult cancer patients after SCOTUS decision

by American Cancer SocietyCredit: Pixabay/CC0 Public DomainThe Supreme Court of the United States (SCOTUS) ruling in Dobbs vs. Jackson overruled Roe vs. Wade, returning an individual's right

Continued access to fertility preservation is critical for teens and young adult cancer patients after SCOTUS decision

by American Cancer SocietyCredit: Pixabay/CC0 Public DomainThe Supreme Court of the United States (SCOTUS) ruling in Dobbs vs. Jackson overruled Roe vs. Wade, returning an individual's right
The rising burden of respiratory tract cancer in Asia

The rising burden of respiratory tract cancer in Asia

by Cactus CommunicationsTrends in age-standardized rates of TBL cancer, 1990–2019. Deaths for males, females, and both sexes combined; DALYs for males, females, and both sexes combined; and incidence

The rising burden of respiratory tract cancer in Asia

by Cactus CommunicationsTrends in age-standardized rates of TBL cancer, 1990–2019. Deaths for males, females, and both sexes combined; DALYs for males, females, and both sexes combined; and incidence
Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in

Study reveals somatic mutation profile of colorectal tumor with simultaneous APC and MLH1 germline mutations

by Zhao Weiwei; Hong Bo, Hefei Institutes of Physical Science, Chinese Academy of SciencesThe pedigree of the studied family, and hematoxylin-eosin staining of colorectal adenocarcinoma or adenomas in