New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

A two-for-one approach to boost melanoma immunotherapy

by Sanford Burnham Prebys Medical Discovery InstituteCredit: Unsplash/CC0 Public DomainNew research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may gu

Updated on: February 03,2024

A two-for-one approach to boost melanoma immunotherapy

by Sanford Burnham Prebys Medical Discovery InstituteCredit: Unsplash/CC0 Public DomainNew research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may gu

Updated on:February 03,2024

Researchers move closer to 'magic' cancer treatment

by Brent Wittmeier,University of AlbertaU of A researcher Khaled Barakat with the IBM supercomputer his team used to develop a small molecule that could help the body fight cancer by allowing th

Updated on: June 15,2024

Researchers move closer to 'magic' cancer treatment

by Brent Wittmeier,University of AlbertaU of A researcher Khaled Barakat with the IBM supercomputer his team used to develop a small molecule that could help the body fight cancer by allowing th

Updated on:June 15,2024

New machine learning model improves prediction of prostate cancer recurrence

byElsevierCredit: Pixabay/CC0 Public DomainPredicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostat

Updated on: January 11,2024

New machine learning model improves prediction of prostate cancer recurrence

byElsevierCredit: Pixabay/CC0 Public DomainPredicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostat

Updated on:January 11,2024

Fingertip-sized sensors to prevent skin cancer

by FreshscienceNoushin is looking to trial her UV sensor in the field by 2022.Credit: Dr Leila KhanjaniBetween your morning commute, coffee break, playing with the kids, or mowing the lawn—how d

Updated on: April 10,2024

Fingertip-sized sensors to prevent skin cancer

by FreshscienceNoushin is looking to trial her UV sensor in the field by 2022.Credit: Dr Leila KhanjaniBetween your morning commute, coffee break, playing with the kids, or mowing the lawn—how d

Updated on:April 10,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on: April 18,2024

Study sheds light on the function of a long-mysterious PCSK9 mutation

by American Society for Biochemistry and Molecular BiologyCredit: CC0 Public DomainHigh levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading ris

Updated on:April 18,2024

Researchers pinpoint why lymphoma patients may become resistant to specific therapy

by H. Lee Moffitt Cancer Center & Research InstituteHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0With more targeted

Updated on: June 01,2024

Researchers pinpoint why lymphoma patients may become resistant to specific therapy

by H. Lee Moffitt Cancer Center & Research InstituteHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0With more targeted

Updated on:June 01,2024

Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ

Updated on: January 02,2024

Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ

Updated on:January 02,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on: February 18,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on:February 18,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on: May 20,2024

How a specific metabolite tells cells whether to repair DNA

by Anna Megdell,University of MichiganCredit: CC0 Public DomainMetabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy

Updated on:May 20,2024

Redefining colorectal cancer subtypes

by The City University of New YorkCredit: The City University of New YorkThere is a long-standing belief that colorectal cancer (CRC), which causes some 50,000 deaths in the United States each ye

Updated on: April 07,2024

Redefining colorectal cancer subtypes

by The City University of New YorkCredit: The City University of New YorkThere is a long-standing belief that colorectal cancer (CRC), which causes some 50,000 deaths in the United States each ye

Updated on:April 07,2024

Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on: August 28,2024

Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on:August 28,2024