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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers identify potential target in myeloid malignancies

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp
'Dead zone' within tumor promotes cancer spread, helped by a protein secreted by cancer cells

'Dead zone' within tumor promotes cancer spread, helped by a protein secreted by cancer cells

by Diana Mapes, Fred Hutchinson Cancer CenterFred Hutch's Ami Yamamoto, foreground, at work in the lab of Dr. Kevin Cheung (seen in background). Yamamoto's investigation of the necrotic core o

'Dead zone' within tumor promotes cancer spread, helped by a protein secreted by cancer cells

by Diana Mapes, Fred Hutchinson Cancer CenterFred Hutch's Ami Yamamoto, foreground, at work in the lab of Dr. Kevin Cheung (seen in background). Yamamoto's investigation of the necrotic core o
Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H

Insurance status mediates racial, ethnic inequities in cervical cancer, finds study

by Elana GotkineInsurance status mediates racial and ethnic inequities in advanced-stage cervical cancer diagnosis, according to a study published online March 10 inJAMA Network Open.Hunter K. H
Greater prevalence of anal cancer precursors for women living with HIV than prior reports

Greater prevalence of anal cancer precursors for women living with HIV than prior reports

by Boston Medical CenterCredit: CC0 Public DomainThe prevalence of anal high-grade squamous intraepithelial lesions (HSIL), which precede anal cancer, is much higher in women living with HIV than

Greater prevalence of anal cancer precursors for women living with HIV than prior reports

by Boston Medical CenterCredit: CC0 Public DomainThe prevalence of anal high-grade squamous intraepithelial lesions (HSIL), which precede anal cancer, is much higher in women living with HIV than
Experts boost activity of potential therapeutic target in triple-negative breast cancer

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ
Researchers identify protein that controls CAR T cell longevity

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription
Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

by University of KansasA new University of Kansas research effort featured in the current edition of Integrative Biology has resulted in a low-cost, reliable blood test that uses a small plastic

Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

by University of KansasA new University of Kansas research effort featured in the current edition of Integrative Biology has resulted in a low-cost, reliable blood test that uses a small plastic
Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification
Improving health outcomes with a little help from our friends—and artificial intelligence

Improving health outcomes with a little help from our friends—and artificial intelligence

by Medical University of South CarolinaDr. Chanita Hughes-Halbert of the Medical University of South Carolina and Hollings Cancer Center studies social determinants of health and health dispariti

Improving health outcomes with a little help from our friends—and artificial intelligence

by Medical University of South CarolinaDr. Chanita Hughes-Halbert of the Medical University of South Carolina and Hollings Cancer Center studies social determinants of health and health dispariti
New method to determine before surgery which prostate tumors pose a lethal threat

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic
Leveraging the power of iPS cell technology to study myeloid neoplasm

Leveraging the power of iPS cell technology to study myeloid neoplasm

byKyoto UniversityCredit:British Journal of Haematology(2024). DOI: 10.1111/bjh.19720Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rea

Leveraging the power of iPS cell technology to study myeloid neoplasm

byKyoto UniversityCredit:British Journal of Haematology(2024). DOI: 10.1111/bjh.19720Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rea
Can some cancer patients safely skip radiation therapy? New studies say yes

Can some cancer patients safely skip radiation therapy? New studies say yes

by Dennis ThompsonRadiation therapy might not be necessary in treating some forms of rectal cancer and lymphoma, sparing patients from the toxic treatment, a pair of new clinical trials shows.One tria

Can some cancer patients safely skip radiation therapy? New studies say yes

by Dennis ThompsonRadiation therapy might not be necessary in treating some forms of rectal cancer and lymphoma, sparing patients from the toxic treatment, a pair of new clinical trials shows.One tria