Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on: May 25,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on:May 25,2024

Study finds 'startling' inequities in end-of-life opioid treatment

byHarvard UniversityCredit: Unsplash/CC0 Public DomainOlder Black and Hispanic patients with advanced cancer are less likely than white patients to receive opioid medications for pain relief in

Updated on: January 23,2024

Study finds 'startling' inequities in end-of-life opioid treatment

byHarvard UniversityCredit: Unsplash/CC0 Public DomainOlder Black and Hispanic patients with advanced cancer are less likely than white patients to receive opioid medications for pain relief in

Updated on:January 23,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on: July 05,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on:July 05,2024

Deadly 'two-faced' protein drives cancer growth, cripples T-cell avengers

by Delthia Ricks , Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDScientists have deciphered a key st

Updated on: April 09,2024

Deadly 'two-faced' protein drives cancer growth, cripples T-cell avengers

by Delthia Ricks , Medical XpressScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDScientists have deciphered a key st

Updated on:April 09,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on: August 28,2024

Novel approach to study hypoxia enables identification of a marker for ovarian cancers

by Myreille Larouche,University of MontrealLong-term severe hypoxia adaptation induces EMT-like morphological changes. Credit:Cancer Gene Therapy(2024). DOI: 10.1038/s41417-024-00795

Updated on:August 28,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on: March 30,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on:March 30,2024

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma

by St. Jude Children's Research HospitalInvestigators at St. Jude Children's Research Hospital have linked inherited BRCA2 gene mutations with an increased risk of non-Hodgkin lymphoma in

Updated on: May 13,2024

Inherited BRCA2 mutations linked to increased risk of childhood lymphoma

by St. Jude Children's Research HospitalInvestigators at St. Jude Children's Research Hospital have linked inherited BRCA2 gene mutations with an increased risk of non-Hodgkin lymphoma in

Updated on:May 13,2024

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost

Updated on: January 12,2024

New mathematical model shows promising results for prostate cancer treatment

byUniversity of PortsmouthGraphical abstract. Credit:Mathematical Biosciences(2022). DOI: 10.1016/j.mbs.2022.108940A new mathematical model which aims to optimize treatment for prost

Updated on:January 12,2024

Researchers ID novel treatment pathway for deadly pancreatic cancers

by Johns Hopkins University School of MedicineThe High Mobility Group A1 (HMGA1) protein functions as a "molecular switch" that "flips on" expression and secretion of a critic

Updated on: February 03,2024

Researchers ID novel treatment pathway for deadly pancreatic cancers

by Johns Hopkins University School of MedicineThe High Mobility Group A1 (HMGA1) protein functions as a "molecular switch" that "flips on" expression and secretion of a critic

Updated on:February 03,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on: January 07,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on:January 07,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on: January 30,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on:January 30,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on: April 09,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on:April 09,2024