Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on: September 27,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on:September 27,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on: April 07,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on:April 07,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on: April 18,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on:April 18,2024

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys

Updated on: March 06,2024

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys

Updated on:March 06,2024

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Updated on: March 12,2024

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Updated on:March 12,2024

A new drug prevents epithelial-mesenchymal transition, metastasis and resistance to anti-cancer therapy

by Université libre de BruxellesTargeting netrin-1 reduces metastasis and sensitizes tumor cells to chemotherapy in skin SCC.a, Dot plot showing the number of spontaneous lung metastases in

Updated on: January 30,2024

A new drug prevents epithelial-mesenchymal transition, metastasis and resistance to anti-cancer therapy

by Université libre de BruxellesTargeting netrin-1 reduces metastasis and sensitizes tumor cells to chemotherapy in skin SCC.a, Dot plot showing the number of spontaneous lung metastases in

Updated on:January 30,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on: February 01,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on:February 01,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on: January 30,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on:January 30,2024

First-line regimens with endocrine therapy show benefits in breast cancer

by Lori SolomonFirst-line regimens with endocrine therapy (ET) may be associated with benefits among patients with human epidermal growth factor receptor 2-positive (ERBB2-positive [formerly HER2-posi

Updated on: February 03,2024

First-line regimens with endocrine therapy show benefits in breast cancer

by Lori SolomonFirst-line regimens with endocrine therapy (ET) may be associated with benefits among patients with human epidermal growth factor receptor 2-positive (ERBB2-positive [formerly HER2-posi

Updated on:February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024