Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on: August 03,2024 0

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on:August 03,2024 0

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f

Updated on: July 08,2024 0

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f

Updated on:July 08,2024 0

Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on: February 23,2024 17

Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on:February 23,2024 17

Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on: May 23,2024 4

Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on:May 23,2024 4

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on: May 23,2024 7

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth

Updated on:May 23,2024 7

Study: Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

by American Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainA new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives

Updated on: February 18,2024 18

Study: Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

by American Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainA new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives

Updated on:February 18,2024 18

Branched-chain amino acids regulate the development and progression of cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeFigure 1. Credit: Agency for Science, Technology and Research (A*STAR), SingaporeResearchers at A*STAR's Singapore Bioimaging

Updated on: April 14,2024 14

Branched-chain amino acids regulate the development and progression of cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeFigure 1. Credit: Agency for Science, Technology and Research (A*STAR), SingaporeResearchers at A*STAR's Singapore Bioimaging

Updated on:April 14,2024 14

Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

by European Academy of Dermatology and VenereologyCredit: CC0 Public DomainVitamin D levels affect overall survival for melanoma (skin cancer) patients, a new study presented at the 31stEuropean

Updated on: January 30,2024 16

Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

by European Academy of Dermatology and VenereologyCredit: CC0 Public DomainVitamin D levels affect overall survival for melanoma (skin cancer) patients, a new study presented at the 31stEuropean

Updated on:January 30,2024 16

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024 3

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024 3

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit

Updated on: May 13,2024 6

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit

Updated on:May 13,2024 6

Support for home cancer testing

by Flinders UniversityCredit: Pixabay/CC0 Public DomainScreening for bowel cancer using at-home fecal immunochemical tests could help to reduce the frequency of colonoscopies for some at above-av

Updated on: January 30,2024 10

Support for home cancer testing

by Flinders UniversityCredit: Pixabay/CC0 Public DomainScreening for bowel cancer using at-home fecal immunochemical tests could help to reduce the frequency of colonoscopies for some at above-av

Updated on:January 30,2024 10

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks

Updated on: May 13,2024 3

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks

Updated on:May 13,2024 3