Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on: January 08,2024

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on:January 08,2024

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on: January 08,2024

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on:January 08,2024

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on: December 21,2023

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on:December 21,2023

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe

Updated on: October 12,2023

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe

Updated on:October 12,2023

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Updated on: November 01,2023

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Updated on:November 01,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on: October 11,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on:October 11,2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody

Updated on: October 31,2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody

Updated on:October 31,2023

AI beats human breast cancer diagnosis

by Patrick GaleyBreast scans are recommended for women above 50 who exhibit no signs of cancerA computer programme can identify breast cancer from routine scans with greater accuracy than human expert

Updated on: December 20,2023

AI beats human breast cancer diagnosis

by Patrick GaleyBreast scans are recommended for women above 50 who exhibit no signs of cancerA computer programme can identify breast cancer from routine scans with greater accuracy than human expert

Updated on:December 20,2023

Scientists find 'unknown link' between lung cancer and common parasite

by University of SalfordA picture of Toxoplasma infected cells in lung tissue.The brown-stained cells are those that contain the parasite. Credit: University of SalfordToxoplasma gondii, a micros

Updated on: March 12,2024

Scientists find 'unknown link' between lung cancer and common parasite

by University of SalfordA picture of Toxoplasma infected cells in lung tissue.The brown-stained cells are those that contain the parasite. Credit: University of SalfordToxoplasma gondii, a micros

Updated on:March 12,2024

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on: October 11,2023

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on:October 11,2023

Elle Macpherson says she refused chemotherapy after breast cancer diagnosis—here's what oncologists think

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainAfter being diagnosed with breast cancer seven years ago, Elle Macpherson made a controversial choice: She refused chemotherapy, the mode

Updated on: September 27,2024

Elle Macpherson says she refused chemotherapy after breast cancer diagnosis—here's what oncologists think

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainAfter being diagnosed with breast cancer seven years ago, Elle Macpherson made a controversial choice: She refused chemotherapy, the mode

Updated on:September 27,2024

IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on: October 10,2023

IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on:October 10,2023