Leukemia vulnerability discovered causing drug sensitivity

byJosep Carreras Leukaemia Research InstituteCells from acute lymphoblastic leukemia, a disease against which treatment with glutathione inhibitors has demonstrated preclinical efficacy, dying b

Updated on: December 22,2023

Leukemia vulnerability discovered causing drug sensitivity

byJosep Carreras Leukaemia Research InstituteCells from acute lymphoblastic leukemia, a disease against which treatment with glutathione inhibitors has demonstrated preclinical efficacy, dying b

Updated on:December 22,2023

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on: December 21,2023

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on:December 21,2023

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on: December 20,2023

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on:December 20,2023

Research reveals how synthesized plankton molecules inhibit cancer proteins

by Justin Jackson , Medical Xpressa, Chemical structure of reported PA and PB (in beige), and the revised structure of PB (in blue) in this work. b, A retrosynthesis targeting a minimally oxidized int

Updated on: October 14,2023

Research reveals how synthesized plankton molecules inhibit cancer proteins

by Justin Jackson , Medical Xpressa, Chemical structure of reported PA and PB (in beige), and the revised structure of PB (in blue) in this work. b, A retrosynthesis targeting a minimally oxidized int

Updated on:October 14,2023

How Even Moderate Alcohol Consumption Can Increase Your Risk

Alcohol consumption is a common practice in many cultures, often associated with social gatherings and celebrations.

Updated on: March 14,2025

How Even Moderate Alcohol Consumption Can Increase Your Risk

Alcohol consumption is a common practice in many cultures, often associated with social gatherings and celebrations.

Updated on:March 14,2025

Carbon oxide gas boosts photothermal therapy under mild temperature

by ZHANG Nannan,Chinese Academy of SciencesSchematic illustration of (A) synthesis route of mPEG(CO) and (B) the nanobomb consist of mPEG(CO) and PBPTV. (C) Schematic illustration of low-tempera

Updated on: December 22,2023

Carbon oxide gas boosts photothermal therapy under mild temperature

by ZHANG Nannan,Chinese Academy of SciencesSchematic illustration of (A) synthesis route of mPEG(CO) and (B) the nanobomb consist of mPEG(CO) and PBPTV. (C) Schematic illustration of low-tempera

Updated on:December 22,2023

Sweden sees skin cancer decline in under-50s for 1st time: Study

Credit: Anna Tarazevich from PexelsSkin cancer is declining among younger adults in Sweden for the first time after decades of increases, making it the first European country to see a fall, researcher

Updated on: September 27,2024

Sweden sees skin cancer decline in under-50s for 1st time: Study

Credit: Anna Tarazevich from PexelsSkin cancer is declining among younger adults in Sweden for the first time after decades of increases, making it the first European country to see a fall, researcher

Updated on:September 27,2024

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on: December 21,2023

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on:December 21,2023

Patients prefer stool test to colonoscopy

byCedars-Sinai Medical CenterGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.07.012Three-quarters of people prefer to do a fecal im

Updated on: December 19,2023

Patients prefer stool test to colonoscopy

byCedars-Sinai Medical CenterGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.07.012Three-quarters of people prefer to do a fecal im

Updated on:December 19,2023

After Pembrolizumab/Lenvatinab Provides Clinical Benefit in Previously Treated Endometrial Cancer

October 23, 2023Dylann Cohn-EmeryContinued treatment with lenvatinib monotherapy after the completeion of combination therapy with pembrolizumab and lenvatinib resulted in sustained clinical benefit v

Updated on: October 24,2023

After Pembrolizumab/Lenvatinab Provides Clinical Benefit in Previously Treated Endometrial Cancer

October 23, 2023Dylann Cohn-EmeryContinued treatment with lenvatinib monotherapy after the completeion of combination therapy with pembrolizumab and lenvatinib resulted in sustained clinical benefit v

Updated on:October 24,2023

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on: October 30,2023

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on:October 30,2023

Novel cell 'switches' found to promote lung cancer growth, treatment resistance

by Melissa Rohman,Northwestern UniversitySCLC cell lines have divergent gene regulatory networks and phenotypes. (A) Hierarchical clustering was performed using 53 SCLC cell lines. Silhouette wi

Updated on: December 21,2023

Novel cell 'switches' found to promote lung cancer growth, treatment resistance

by Melissa Rohman,Northwestern UniversitySCLC cell lines have divergent gene regulatory networks and phenotypes. (A) Hierarchical clustering was performed using 53 SCLC cell lines. Silhouette wi

Updated on:December 21,2023