Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on: December 20,2023

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on:December 20,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on: April 27,2024

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on:April 27,2024

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on: December 19,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on:December 19,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023

Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on: December 10,2024

Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on:December 10,2024

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on: December 19,2023

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on:December 19,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on: December 21,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on:December 21,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on: December 20,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on:December 20,2023

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on: December 19,2023

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on:December 19,2023

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on: December 19,2023

Immunotherapy Combo Boosts Survival in Metastatic Melanoma

byColleen Fleisson August 19, 2023For patients diagnosed with advancedmetastatic melanomathat does not respond to the commonly utilized PD-1 inhibitors, immunotherapy drugs ipi

Updated on:December 19,2023