IBIS-II study finds anastrozole reduces breast cancer rates for high risk postmenopausal women

byQueen Mary, University of LondonCredit: CC0 Public DomainThe Queen Mary University of London professor leading an international breast cancer study says anastrozole—rather than tamoxifen—shoul

Updated on: December 22,2023

IBIS-II study finds anastrozole reduces breast cancer rates for high risk postmenopausal women

byQueen Mary, University of LondonCredit: CC0 Public DomainThe Queen Mary University of London professor leading an international breast cancer study says anastrozole—rather than tamoxifen—shoul

Updated on:December 22,2023

Breaking down proteins: How starving cancer cells switch food sources

byGerman Cancer Research CenterHuman cancer cells (cell nucleus in blue) feeding on protein (Albumin, labeled in green). The proteins are digested and broken down into amino acids in the lysosom

Updated on: December 22,2023

Breaking down proteins: How starving cancer cells switch food sources

byGerman Cancer Research CenterHuman cancer cells (cell nucleus in blue) feeding on protein (Albumin, labeled in green). The proteins are digested and broken down into amino acids in the lysosom

Updated on:December 22,2023

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on: August 12,2024

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on:August 12,2024

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Updated on: August 03,2024

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Updated on:August 03,2024

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w

Updated on: January 04,2024

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w

Updated on:January 04,2024

Liver cancer research: Iron-dependent cell death could be key to novel combination therapies

byGoethe University Frankfurt am MainThe light microscope image shows the liver of a diseased mouse in which many tumours have formed. The tumours are slightly darker in colour, have a rounded s

Updated on: December 22,2023

Liver cancer research: Iron-dependent cell death could be key to novel combination therapies

byGoethe University Frankfurt am MainThe light microscope image shows the liver of a diseased mouse in which many tumours have formed. The tumours are slightly darker in colour, have a rounded s

Updated on:December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on: December 22,2023

Combination of chemo and diabetes drugs shows potential for treating Ewing sarcoma

byHouston MethodistStephen T. Wong, Ph.D., Associate Director, Cores, Biostatistics and BioinformaticsHouston Methodist Cancer Center. Credit: Houston MethodistEwing sarcoma, an aggressive tumor

Updated on:December 22,2023

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on: December 20,2023

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on:December 20,2023

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on: December 19,2023

Ultrasound activated microbubbles enhance the activity of standard of care therapeutics in pancreatic cancer

byTranslational Genomics Research InstituteUltrasound administration setup and drug dosing timeline. A. Photograph of the ultrasound administration setup; B. Schematic depiction of the ultrasoun

Updated on:December 19,2023

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on: December 22,2023

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on:December 22,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on: December 27,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on:December 27,2023

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on: January 04,2024

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on:January 04,2024