Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on: December 26,2023

Precision oncology approach shows potential for high grade gliomas harboring a genetic mutation

by Nicole Fawcett,University of MichiganImmunostaining in a genetically engineered pediatric high grade glioma model harboring the H3-G34R mutation. Tumor cells are shown in green, nuclei in blu

Updated on:December 26,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B

Updated on: December 27,2023

Scientists identify multiple cell types that may contribute to treatment resistance in prostate cancer

byeLifeA cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC B

Updated on:December 27,2023

Huge delays in dealing with complaints against UK drug companies revealed

by British Medical JournalCredit: Pixabay/CC0 Public DomainProcessing times for complaints against drug companies suspected of having breached their industry code of practice have more than tripl

Updated on: April 23,2024

Huge delays in dealing with complaints against UK drug companies revealed

by British Medical JournalCredit: Pixabay/CC0 Public DomainProcessing times for complaints against drug companies suspected of having breached their industry code of practice have more than tripl

Updated on:April 23,2024

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on: December 22,2023

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on:December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on: December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on:December 22,2023

How cancer cells move and metastasize is influenced by the fluids surrounding them

by Yizeng Li,The ConversationCredit: CC0 Public DomainCell migration, or how cells move in the body, is essential to both normal body function and disease progression. Cell movement is what allo

Updated on: December 18,2023

How cancer cells move and metastasize is influenced by the fluids surrounding them

by Yizeng Li,The ConversationCredit: CC0 Public DomainCell migration, or how cells move in the body, is essential to both normal body function and disease progression. Cell movement is what allo

Updated on:December 18,2023

Old drugs offer new ways of treating bowel cancer

byUniversity of AucklandCredit: CC0 Public DomainOld medicines, combined in new ways, are showing promise for treating bowel cancer, a group of University of Auckland researchers has found.&quot

Updated on: December 26,2023

Old drugs offer new ways of treating bowel cancer

byUniversity of AucklandCredit: CC0 Public DomainOld medicines, combined in new ways, are showing promise for treating bowel cancer, a group of University of Auckland researchers has found.&quot

Updated on:December 26,2023

Developing AI tools for breast cancer precision pathology

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainBreast cancer is the most common cancer type in women globally, but there is a continuous decline in mortality rates. A partial explanatio

Updated on: December 26,2023

Developing AI tools for breast cancer precision pathology

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainBreast cancer is the most common cancer type in women globally, but there is a continuous decline in mortality rates. A partial explanatio

Updated on:December 26,2023

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on: December 20,2023

Flipping the switch: Scientists shed new light on genetic changes that turn 'on' cancer genes

bySalk InstituteWhen genetic mutations cause chromosomes to break apart and fuse together in different ways, normal cells can become cancerous. In this image, normal chromosomes (blue) are shown

Updated on:December 20,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023