Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on: March 01,2024 14

Without 'yoga and chardonnay' leukemia stem cells are stressed to death

by CU Anschutz Medical CampusCraig T. Jordan, Ph.D., and colleagues show that blocking the stress-relief of mitophagy kills leukemia stem cells without harming healthy blood stem cells. Credit: U

Updated on:March 01,2024 14

Drug combination prompts immune response in some resistant pancreatic cancers

byJohns Hopkins University School of MedicineRadiologic scans and change in CA19.9 of the three responders during the course of entinostat plus nivolumab therapy. Credit:Nature Communicati

Updated on: December 01,2024 0

Drug combination prompts immune response in some resistant pancreatic cancers

byJohns Hopkins University School of MedicineRadiologic scans and change in CA19.9 of the three responders during the course of entinostat plus nivolumab therapy. Credit:Nature Communicati

Updated on:December 01,2024 0

Pembrolizumab aids survival with high-risk endometrial cancer

by Lori SolomonPembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published onl

Updated on: November 09,2024 0

Pembrolizumab aids survival with high-risk endometrial cancer

by Lori SolomonPembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published onl

Updated on:November 09,2024 0

A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on: May 23,2024 4

A curiosity-driven genetic discovery that should impact cancer treatments

by Trinity College DublinKiller T cells surround a cancer cell. Credit: NIHA team of geneticists with a desire to understand the inner workings of genes implicated in cellular identity has discov

Updated on:May 23,2024 4

New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on: January 12,2024 12

New cancer drug candidate targets immune system 'brakes'

by Sarah C.P. Williams,University of ChicagoDesign and synthesis of stapled alpha-helical peptides targeting FOXP3. (A) Human FOXP3 sequence. Residues F214–K263 represent the entirety of a helix

Updated on:January 12,2024 12

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on: April 18,2024 10

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on:April 18,2024 10

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024 16

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024 16

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on: April 22,2024 14

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on:April 22,2024 14

Newly discovered link between FBXW7 mutations and EGFR signaling in colorectal cancer

by Hubrecht InstituteTwo microscopy images of human colon organoids. The left image shows an organoid with the FBXW7 mutation (colorectal cancer), and the right image shows an organoid without th

Updated on: March 30,2024 0

Newly discovered link between FBXW7 mutations and EGFR signaling in colorectal cancer

by Hubrecht InstituteTwo microscopy images of human colon organoids. The left image shows an organoid with the FBXW7 mutation (colorectal cancer), and the right image shows an organoid without th

Updated on:March 30,2024 0

Computational tool reveals untapped efficacy of cancer drug, leveling up cancer fight

byPurdue UniversityBenchmark for evaluating and optimizing existing pathway analysis methods. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51859-9Research from Purdue

Updated on: September 28,2024 0

Computational tool reveals untapped efficacy of cancer drug, leveling up cancer fight

byPurdue UniversityBenchmark for evaluating and optimizing existing pathway analysis methods. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51859-9Research from Purdue

Updated on:September 28,2024 0

Poor oral health linked to a 75% increase in liver cancer risk, new study finds

by SAGE PublicationsCredit: CC0 Public DomainThe study, by researchers at Queen's University Belfast, analysed a large cohort of over 469,000 people in the UK, investigated the association be

Updated on: May 21,2024 3

Poor oral health linked to a 75% increase in liver cancer risk, new study finds

by SAGE PublicationsCredit: CC0 Public DomainThe study, by researchers at Queen's University Belfast, analysed a large cohort of over 469,000 people in the UK, investigated the association be

Updated on:May 21,2024 3

Chemotherapy can be a challenging treatment—here's how to deal with some of the side-effects

by Justin Stebbing,The ConversationCredit: Ivan Samkov from PexelsChemotherapy is a powerful cancer medication—but it can also be a very challenging treatment. It works by killing fast-growing c

Updated on: November 10,2024 0

Chemotherapy can be a challenging treatment—here's how to deal with some of the side-effects

by Justin Stebbing,The ConversationCredit: Ivan Samkov from PexelsChemotherapy is a powerful cancer medication—but it can also be a very challenging treatment. It works by killing fast-growing c

Updated on:November 10,2024 0